1785666-54-7
Chemical Structure
(E/Z)-Daporinad hydrochloride
Synonym(s): (E/Z)-FK866 hydrochloride; (E/Z)-APO866 hydrochloride
- CAS No.: 1785666-54-7
- Formula:C24H30ClN3O2
- Molecular Weight:427.97
IUPAC Name: (E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide hydrochloride
InChIKey: MULSIBUGDPOSHV-CALJPSDSSA-N
SMILES: O=C(N1CCC(CC1)CCCCNC(/C=C/C2=CN=CC=C2)=O)C3=CC=CC=C3.Cl
Biological Activity: (E/Z)-Daporinad hydrochloride ((E/Z)-FK866 hydrochloride) is a potent inhibitor of nicotinamide phosphoribose transferase (NAMPT). (E/Z)-Daporinad hydrochloride induces apoptosis by specifically inhibiting NAMPT to gradually deplete intracellular NAD+. (E/Z)-Daporinad hydrochloride can be used in the study of cancer biology and inflammatory diseases[1].
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(E/Z)-Daporinad hydrochloride | (E/Z)-Daporinad hydrochloride ((E/Z)-FK866 hydrochloride) is a potent inhibitor of nicotinamide phosphoribose transferase (NAMPT). (E/Z)-Daporinad hydrochloride induces apoptosis by specifically inhibiting NAMPT to gradually deplete intracellular NAD+. (E/Z)-Daporinad hydrochloride can be used in the study of cancer biology and inflammatory diseases. | |||||||||||||||||||||
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