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Cat. No.: HY-N2319R

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Dihydroergocristine mesylate (Standard)

Name: Dihydroergocristine mesylate (Standard)
Brand: MedChemExpress
SKU: HY-N2319R
Availability: PreOrder

(Synonyms: DHEC mesylate (Standard))

Dihydroergocristine (mesylate) (Standard) is the analytical standard of Dihydroergocristine (mesylate). This product is intended for research and analytical applications. Dihydroergocristine mesylate (DHEC mesylate) is a inhibitor of γ-secretase (GSI), reduces the production of the Alzheimer's disease amyloid-β peptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation constants (K_d) of 25.7 nM and 9.8 μM, respectively.

For research use only. We do not sell to patients.

CAS No.: 24730-10-7
Formula: C₃₆H₄₅N₅O₈S
Molecular Weight:707.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dihydroergocristine mesylate (Standard) Chemical Structure

CAS No.: 24730-10-7

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 24730-10-7
Molecular Weight 707.84
Formula C₃₆H₄₅N₅O₈S
SMILES

O[C@@]([C@@](CCC1)([H])N1C2=O)(O[C@](NC([C@@H](CN(C)[C@]3([H])C4)C[C@]3([H])C5=C6C4=CNC6=CC=C5)=O)(C(C)C)C7=O)N7[C@H]2CC8=CC=CC=C8.CS(=O)(O)=O
Synonyms

DHEC mesylate (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Lei X, et al. The FDA-approved natural product dihydroergocristine reduces the production of the Alzheimer's disease amyloid-β peptides. Sci Rep. 2015 Nov 16;5:16541. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Dihydroergocristine mesylate (Standard)

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Dihydroergocristine mesylate (Standard)