PSTK - phosphoseryl-tRNA kinase Gene

Also Known as C10orf89

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 118672

About PSTK

Cytogenetic location: 10q26.13 Genomic coordinates (GRCh38): 10:122,980,401-122,990,390 (from NCBI)

This gene has 9 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in bone marrow (RPKM 1.8), testis (RPKM 1.5) and 25 other tissues.

Summary

Predicted to enable kinase activity and tRNA binding activity. Predicted to be involved in phosphorylation; selenocysteinyl-tRNA(Sec) biosynthetic process; and translation. Predicted to act upstream of or within selenocysteine incorporation. [provided by Alliance of Genome Resources, Apr 2022]

PSTK Products (2)

mRNA Protein Name
NM_001363531.2 NP_001350460.1 L-seryl-tRNA(Sec) kinase isoform 1
NM_153336.3 NP_699167.2 L-seryl-tRNA(Sec) kinase isoform 2

PSTK Protein Structure

KTI12

KTI12: Chromatin associated protein KTI12 (20 - 57)

KTI12

KTI12: Chromatin associated protein KTI12 (138 - 296)

  • 0
  • 100
  • 200
  • 300
  • 348 a.a.
Protein Preferred Names Protein Names

L-seryl-tRNA(Sec) kinase

  • O-phosphoseryl-tRNA(Sec) kinase

Related Diseases

Diseases Alias
Keshan Disease

  • Caused By Deficiency Of Selenium In The Diet

  • Enlarged Heart And Poor Heart Function
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11344 PSTK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20803 Pstk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27317 Pstk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta PSTK VGNC VGNC:76335
Mus musculus PSTK MGD MGI:2685945
Bos taurus PSTK VGNC VGNC:33485
Felis catus PSTK VGNC VGNC:64419
Canis familiaris PSTK VGNC VGNC:45126
Rattus norvegicus PSTK RGD RGD:1564300
Others PSTK NCBI