DL-α-Tocopherol acetate-13C4,d6
DL-α-Tocopherol acetate-13C4,d6 is the deuterium and 13C labeled DL-α-Tocopherol acetate. DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition.
For research use only. We do not sell to patients.
- Formula: C2713C4H46D6O3
- Molecular Weight:482.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 52225-20-4
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Molecular Weight 482.75
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Formula C2713C4H46D6O3
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SMILES
CC1=C2C(CC[C@](O2)(CCC[C@@H](CCC[C@@H](CCCC(C)C)C)C)C)=C([13C]([2H])([2H])[2H])C(O[13C]([13CH3])=O)=C1[13C]([2H])([2H])[2H]
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Synonyms
Vitamin E acetate-13C4,d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Nagy K, et al. Double-balloon jejunal perfusion to compare absorption of vitamin E and vitamin E acetate in healthy volunteers under maldigestion conditions. Eur J Clin Nutr. 2013 Feb;67(2):202-6. [Content Brief]
[3]. Nishio K, et al. α-Tocopheryl phosphate: uptake, hydrolysis, and antioxidant action in cultured cells and mouse. Free Radic Biol Med. 2011 Jun 1550(12):1794-800. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DL-α-Tocopherol acetate-13C4,d6 Related Classifications
HY-B1278AS Related Classifications
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