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DL-α-Tocopherol acetate (Synonyms: Vitamin E acetate)

Cat. No.: HY-B1278A Purity: >98.0%
Handling Instructions

DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition.

For research use only. We do not sell to patients.

DL-α-Tocopherol acetate Chemical Structure

DL-α-Tocopherol acetate Chemical Structure

CAS No. : 52225-20-4

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of DL-α-Tocopherol acetate:

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Description

DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition.

In Vivo

DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition[1]. DL-α-Tocopherol acetate (α-TA) increases tissue cholesterol levels in liver, brian, testis and herart. The brain cholesterol level is much higher than those in other tissues when adjusted by protein level. DL-α-Tocopherol acetate also increases the level of lipid peroxidation in liver, brain, and testis of mice[2].

Clinical Trial
Molecular Weight

472.74

Formula

C₃₁H₅₂O₃

CAS No.

52225-20-4

SMILES

CC(CCC[[email protected]](CCC[[email protected]](CCC[[email protected]@]1(CCC2=C(C(OC(C)=O)=C(C(C)=C2O1)C)C)C)C)C)C.CC(CCC[[email protected]](C)CCC[[email protected]](C)CCC[[email protected]@]3(C)CCC4=C(C(OC(C)=O)=C(C(C)=C4O3)C)C)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 83.3 mg/mL (176.21 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1153 mL 10.5766 mL 21.1533 mL
5 mM 0.4231 mL 2.1153 mL 4.2307 mL
10 mM 0.2115 mL 1.0577 mL 2.1153 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Animal Administration
[2]

Male mice (specific-pathogen-free, 4 weeks of age) are divided into three groups. They are fed for 4 weeks with the CE2 diet containing one of three different antioxidants, 0.002 wt% DL-α-Tocopherol acetate (α-TA) (n=6), 0.02 wt% α-T (n=6) or 0.02 wt% α-TP(CD3) (n=7), per kilogram of diet. The mice are maintained under standardized conditions of light (7:00 AM to 7:00 PM), temperature (22°C), and humidity (70%). After 4 weeks, they are sacrificed under anesthesia with diethyl ether. The extracted brain, liver, heart, kidney, testis, and lung are homogenized in ice-cold 10 mM phosphate-buffered saline. Blood samples are collected in heparincontaining tubes. The samples are placed on ice immediately after collection. Plasma is obtained by centrifugation at 830 g for 5 min at 4°C and immediately subjected to analysis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References

Purity: >98.0%

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DL-α-Tocopherol acetate
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