1. GPCR/G Protein Neuronal Signaling
  2. Cannabinoid Receptor
  3. Dodec-2E-ene-8,10-diynoic acid isobutylamide

Dodec-2E-ene-8,10-diynoic acid isobutylamide is an alkamide found in Echinacea angustifolia that binds to CB1 (rat Ki = 61.1 μM) and CB2 (mouse Ki = 47.2 μM) cannabinoid receptors. Dodec-2E-ene-8,10-diynoic acid isobutylamide can be used in research on inflammatory diseases.

For research use only. We do not sell to patients.

Dodec-2E-ene-8,10-diynoic acid isobutylamide

Dodec-2E-ene-8,10-diynoic acid isobutylamide Chemical Structure

CAS No. : 120727-29-9

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Description

Dodec-2E-ene-8,10-diynoic acid isobutylamide is an alkamide found in Echinacea angustifolia that binds to CB1 (rat Ki = 61.1 μM) and CB2 (mouse Ki = 47.2 μM) cannabinoid receptors. Dodec-2E-ene-8,10-diynoic acid isobutylamide can be used in research on inflammatory diseases[1][2].

IC50 & Target[1]

rCB1-R

61.1 μM (Ki)

CB2

47.2 μM (Ki)

In Vitro

Dodec-2E-ene-8,10-diynoic acid isobutylamide (Compound 5) binds to rat CB1 membrane receptors with a Ki of 61.1 μM and to mouse CB2 membrane receptors with a Ki of 47.2 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

245.36

Formula

C16H23NO

CAS No.
SMILES

CC#CC#CCCCC/C=C/C(NCC(C)C)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Dodec-2E-ene-8,10-diynoic acid isobutylamide
Cat. No.:
HY-N19807
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