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Cat. No.: HY-158679

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E3 Ligase Ligand-linker Conjugate 110

E3 Ligase Ligand-linker Conjugate 110 is a E3 ligase ligand-linker conjugate, used for the synthesis of PROTAC BcI-2/BcI-xI Degrader-1 (HY-158551).

For research use only. We do not sell to patients.

Formula: C₃₀H₄₀N₄O₈S
Molecular Weight:616.73

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

E3 Ligase Ligand-linker Conjugate 110 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

E3 Ligase Ligand-linker Conjugate 110 is a E3 ligase ligand-linker conjugate, used for the synthesis of PROTAC BcI-2/BcI-xI Degrader-1 (HY-158551)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 616.73
Formula C₃₀H₄₀N₄O₈S
SMILES

O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)CCO4)C4=C2)=O)[C@H](C(C)(C)C)NC(OCCCCCC(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dongping, et al. Chimeric compound used for targeted degradation of bcl-2 protein, preparation method therefor, and pharmaceutical application thereof. Patent. WO2024067818A1.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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E3 Ligase Ligand-linker Conjugate 110

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E3 Ligase Ligand-linker Conjugate 110

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 Ligase Ligand-linker Conjugate 110 Related Classifications

HY-158679 Related Classifications

Bioz

Keywords

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