E3 Ligase Ligand-linker Conjugate 224
E3 Ligase Ligand-linker Conjugate 224 is an E3 Ligase Ligand-Linker Conjugate that incorporates a ligand for VHL (HY-170348) and a PROTAC linker (HY-W895436). E3 Ligase Ligand-linker Conjugate 224 can be used for synthesis of KRAS G12D PROTAC degrader MS243 (HY-181728).
For research use only. We do not sell to patients.
- Formula: C33H49N7O3S
- Molecular Weight:623.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
VHL |
Chemical Information
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Molecular Weight 623.85
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Formula C33H49N7O3S
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SMILES
NCCCCCCCCC1=CN([C@H](C(N2[C@H](C(N[C@@H](C)C3=CC=C(C4=C(C)N=CS4)C=C3)=O)C[C@@H](O)C2)=O)C(C)(C)C)N=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)