EGFR kinase inhibitor 7
EGFR kinase inhibitor 7 (compound 18i) is an EGFR inhibitor (IC50=42.3 nM) with anticancer activity. EGFR kinase inhibitor 7 has significant in vitro cytotoxicity and apoptosis induction ability. EGFR kinase inhibitor 7 has antiproliferative activity against human colon cancer cell line HCT116 and human non-small cell lung cancer cell line A549, with IC50 values of 4.82 µM and 1.43 µM, respectively.
For research use only. We do not sell to patients.
- Formula: C28H26Cl2FN3O3SSe
- Molecular Weight:653.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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EGFR 42.3 nM (IC50) |
Chemical Information
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Molecular Weight 653.45
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Formula C28H26Cl2FN3O3SSe
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SMILES
O=C(C1=C([Se]C2=CC=C(F)C(Cl)=C2)SC(C)=C1C3=CC=CC(Cl)=C3)NC(C)C(N4CCN(C(C=C)=O)CC4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR kinase inhibitor 7 Related Classifications
HY-159512 Related Classifications
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