EGFR WT/T790M-IN-2
EGFR WT/T790M-IN-2 (Compound 7c) is a EGFR T790M/WT inhibitor with IC50 values of 0.08 and 0.13 μM, respectively. EGFR WT/T790M-IN-2 induces apoptosis by blocking the G0-G1 phase (apoptosis). EGFR WT/T790M-IN-2 has antitumor activity.
For research use only. We do not sell to patients.
- Formula: C19H13ClFN5S
- Molecular Weight:397.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
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EGFRT790M 0.08 μM (IC50) |
EGFRWT 0.13 μM (IC50) |
Chemical Information
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Molecular Weight 397.86
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Formula C19H13ClFN5S
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SMILES
N#CC1=C(N=C(N=C1C2=CC=C(F)C=C2)SC)N/N=C/C3=CC(Cl)=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)