Ceratotoxin-2
Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively.
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- No. CAS: 880885-98-3
- Fòrmula: C177H260N52O49S6
- Peso molecular:4092.67
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
IC50: 8 nM (Nav1.2/β1), 88 nM (Nav1.3/β1), 400 nM (Nav1.4/β1), 407 nM (Nav1.1/β1), 1634 nM (Nav1.5/β1)[1]
Chemical Information
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No. CAS 880885-98-3
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Peso molecular 4092.67
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Fòrmula C177H260N52O49S6
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Synonyms
CcoTx2; β-TRTX-cm1b
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Sequence
Asp-Cys-Leu-Gly-Trp-Phe-Lys-Ser-Cys-Asp-Pro-Lys-Asn-Asp-Lys-Cys-Cys-Lys-Asn-Tyr-Thr-Cys-Ser-Arg-Arg-Asp-Arg-Trp-Cys-Lys-Tyr-Tyr-Leu-NH2 (Disulfide bridge:Cys2-Cys17;Cys9-Cys22;Cys16-Cys29)
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Sequence Shortening
DCLGWFKSCDPKNDKCCKNYTCSRRDRWCKYYL-NH2 (Disulfide bridge:Cys2-Cys17;Cys9-Cys22;Cys16-Cys29)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ceratotoxin-2 Related Classifications
HY-P5810 Related Classifications
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