Etidocaine hydrochloride
Based on 2 publication(s) in Google Scholar
Etidocaine (hydrochloride) is a long aminoamide local agent that can suppress or relieve pain.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 36637-19-1
- Formula: C17H29ClN2O
- Molecular Weight:312.88
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Etidocaine hydrochloride
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Biological Activity
IGL-EDC formulations can induce a significant increase in human fibroblasts survival[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Human fibroblasts cells
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Concentration:0, 4, 8, 16, 24 mM
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Incubation Time:4, 6 and 24 h
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Result:Showed that cell survival decreased in a (EDC) concentration with time-dependent manner.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Adult Swiss Webster male mice[2]
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Dosage:0.0075%
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Administration:Etidocaine (spinal injection, 0.0075%, once)
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Result:Did not show postinjection neurologic deficit.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 36637-19-1
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Appearance Solid
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Molecular Weight 312.88
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Formula C17H29ClN2O
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Color White to off-white
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SMILES
[H]Cl.O=C(C(CC)N(CCC)CC)NC1=C(C)C=CC=C1C
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Synonyms
EDC hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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J Nanobiotechnology
RGD-HSA-TAC nanoparticles targeted delivery of tacrolimus and attenuation of podocyte injury in diabetic kidney disease. [Abstract]2025 Feb 4;23(1):81. PMID: 39905421 -
Solvent & Solubility
DMSO : 62.5 mg/mL (199.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Oliveira, et al. Sustained Release from Ionic-Gradient Liposomes Significantly Decreases ETIDOCAINE Cytotoxicity. Pharmaceutical research vol. 35, 12 229. 10 Oct. 2018. [Content Brief]
[2]. Langerman, L, et al. The partition coefficient as a predictor of local anesthetic potency for spinal anesthesia: evaluation of five local anesthetics in a mouse model. Anesthesia and analgesia vol. 79,3 (1994): 490-4. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1961 mL | 15.9806 mL | 31.9611 mL | 79.9028 mL |
| 5 mM | 0.6392 mL | 3.1961 mL | 6.3922 mL | 15.9806 mL | |
| 10 mM | 0.3196 mL | 1.5981 mL | 3.1961 mL | 7.9903 mL | |
| 15 mM | 0.2131 mL | 1.0654 mL | 2.1307 mL | 5.3269 mL | |
| 20 mM | 0.1598 mL | 0.7990 mL | 1.5981 mL | 3.9951 mL | |
| 25 mM | 0.1278 mL | 0.6392 mL | 1.2784 mL | 3.1961 mL | |
| 30 mM | 0.1065 mL | 0.5327 mL | 1.0654 mL | 2.6634 mL | |
| 40 mM | 0.0799 mL | 0.3995 mL | 0.7990 mL | 1.9976 mL | |
| 50 mM | 0.0639 mL | 0.3196 mL | 0.6392 mL | 1.5981 mL | |
| 60 mM | 0.0533 mL | 0.2663 mL | 0.5327 mL | 1.3317 mL | |
| 80 mM | 0.0400 mL | 0.1998 mL | 0.3995 mL | 0.9988 mL | |
| 100 mM | 0.0320 mL | 0.1598 mL | 0.3196 mL | 0.7990 mL |
Etidocaine hydrochloride Related Classifications
HY-B2080A Related Classifications
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