Falecalcitriol

製品番号: HY-32342 純度: 99.90%: Data Sheet SDS COA 取扱説明書
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Falecalcitriol(Fulstan; Hornel) is an analog of calcitriol; has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo.

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Falecalcitriol 構造式

CAS 番号 : 83805-11-2

容量	価格（税別）	在庫状況	数量
1 mg	$320	在庫あり	Estimated Time of Arrival: December 31
5 mg	$950	在庫あり	Estimated Time of Arrival: December 31
10 mg	$1500	在庫あり	Estimated Time of Arrival: December 31
25 mg	$3000	在庫あり	Estimated Time of Arrival: December 31
50 mg	$4800	在庫あり	Estimated Time of Arrival: December 31
100 mg		お問い合わせ
200 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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Based on 0 publication(s) in Google Scholar

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参考文献
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製品説明

Falecalcitriol(Fulstan; Hornel) is an analog of calcitriol; has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo.

分子量

524.58

分子式

C₂₇H₃₈F₆O₃

CAS 番号

83805-11-2

Appearance

Solid

Color

White to off-white

SMILES

C[C@]([C@]/12[H])([C@H](CC2)[C@@H](CCCC(C(F)(F)F)(C(F)(F)F)O)C)CCCC1=C/C=C(C[C@@H](O)C[C@@H]3O)\C3=C

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, protect from light, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (190.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9063 mL	9.5314 mL	19.0629 mL
5 mM	0.3813 mL	1.9063 mL	3.8126 mL
10 mM	0.1906 mL	0.9531 mL	1.9063 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.90%

Select Batch:

データシート (274 KB) SDS (394 KB)

COA (252 KB) HNMR (284 KB) LCMS (103 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Ito H, Ogata H, Yamamoto M, Takahashi K, Shishido K, Takahashi J, Taguchi S, Kinugasa E. Comparison of oral falecalcitriol and intravenous calcitriol in hemodialysis patients with secondary hyperparathyroidism: a randomized, crossover trial. Clin Nephrol. 2009 Jun;71(6):660-8. [Content Brief]

[2]. Tokunaga M, Tamura M, Kabashima N, Serino R, Shibata T, Matsumoto M, Miyamoto T, Miyazaki M, Furuno Y, Takeuchi M, Abe H, Okazaki M, Otsuji Y. Falecalcitriol for conventional vitamin D therapy-resistant secondary hyperparathyroidism in a continuous ambulatory peritoneal dialysis patient. Clin Nephrol. 2008 May;69(5):393-4. [Content Brief]

[3]. Iwao Y, Yamaguchi Y, Fujii K, Toba Y, Asada M, Nagano N, Yamamoto H, Hyoma K, Yamada S, Hirano H, Tone Y, Ohtani H, Saika Y, Fujii R. Long-term suppressive effect of falecalcitriol on parathyroid hormone secretion in secondary hyperparathyroidism in hemodialysis patients.Clin Calcium. 2006 May;16(5):847-51. [Content Brief]

[4]. Morii H. Falecalcitriol as a new therapeutic agent for secondary hyperparathyroidismClin Calcium. 2005 Jan;15(1):29-33. [Content Brief]

[5]. Ohtsuka N, Urayama K. Pharmacological action and clinical effects of falecalcitriol, a highly potent derivative of active vitamin D3.Nihon Yakurigaku Zasshi. 2002 Dec;120(6):427-36. [Content Brief]

[6]. Jean-Pierre Bégué, Danièle Bonnet-Delpon.Recent advances (1995-2005) in fluorinated pharmaceuticals based on natural products. Journal of Fluorine Chemistry.Volume 127, Issue 8, August 2006, Pages 992-1012

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9063 mL	9.5314 mL	19.0629 mL	47.6572 mL
	5 mM	0.3813 mL	1.9063 mL	3.8126 mL	9.5314 mL
	10 mM	0.1906 mL	0.9531 mL	1.9063 mL	4.7657 mL
	15 mM	0.1271 mL	0.6354 mL	1.2709 mL	3.1771 mL
	20 mM	0.0953 mL	0.4766 mL	0.9531 mL	2.3829 mL
	25 mM	0.0763 mL	0.3813 mL	0.7625 mL	1.9063 mL
	30 mM	0.0635 mL	0.3177 mL	0.6354 mL	1.5886 mL
	40 mM	0.0477 mL	0.2383 mL	0.4766 mL	1.1914 mL
	50 mM	0.0381 mL	0.1906 mL	0.3813 mL	0.9531 mL
	60 mM	0.0318 mL	0.1589 mL	0.3177 mL	0.7943 mL
	80 mM	0.0238 mL	0.1191 mL	0.2383 mL	0.5957 mL
	100 mM	0.0191 mL	0.0953 mL	0.1906 mL	0.4766 mL

Falecalcitriol Related Classifications

Metabolic Disease

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量		濃度		体積		分子量 *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）	×	体積 _（開始）	=	濃度 _（終了）	×	体積 _（終了）
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Falecalcitriol83805-11-2VD/VDRVitamin DVitamin D receptorInhibitorinhibitorinhibit

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Falecalcitriol

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Falecalcitriol 関連抗体

おすすめ

•関連スクリーニングライブラリ:

•関連小分子:

•関連タンパク質:

生物活性

純度とドキュメンテーション

参考文献

カスタマーレビュー

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Falecalcitriol Related Classifications

Molarity Calculator

Dilution Calculator

The molarity calculator equation

The dilution calculator equation

Keywords:

最近チェックした製品:

カスタマーレビュー

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