1. Vitamin D Related
  2. VD/VDR
  3. Alfacalcidol

Alfacalcidol (Synonyms: 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3)

Cat. No.: HY-10003 Purity: 99.93%
Handling Instructions

Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis.

For research use only. We do not sell to patients.

Alfacalcidol Chemical Structure

Alfacalcidol Chemical Structure

CAS No. : 41294-56-8

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Free Sample (0.5-1 mg)   Apply now  
5 mg USD 96 In-stock
Estimated Time of Arrival: December 31
10 mg USD 168 In-stock
Estimated Time of Arrival: December 31
50 mg USD 624 In-stock
Estimated Time of Arrival: December 31
100 mg USD 792 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Alfacalcidol:

Top Publications Citing Use of Products
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Description

Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis[1][2][3][4].

IC50 & Target

VDR[2]

Clinical Trial
Molecular Weight

400.64

Formula

C₂₇H₄₄O₂

CAS No.

41294-56-8

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (124.80 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4960 mL 12.4800 mL 24.9601 mL
5 mM 0.4992 mL 2.4960 mL 4.9920 mL
10 mM 0.2496 mL 1.2480 mL 2.4960 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.24 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (6.24 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.24 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.93%

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Alfacalcidol1-hydroxycholecalciferol1.alpha.-Hydroxyvitamin D3VD/VDRVitamin DVitamin D receptorInhibitorinhibitorinhibit

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Product name:
Alfacalcidol
Cat. No.:
HY-10003
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