Alfacalcidol-d6
Based on 1 Customer Validation
Alfacalcidol-d6 is the deuterium labeled Alfacalcidol. Alfacalcidol is a non-selective VDR activator.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 1641940-94-4
- Formula: C27H38D6O2
- Molecular Weight:406.67
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 1641940-94-4
-
Unlabeled Cas 41294-56-8
-
Appearance Solid
-
Molecular Weight 406.67
-
Formula C27H38D6O2
-
Color White to off-white
-
SMILES
O[C@H](C/1=C)C[C@H](O)CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCCC(C([2H])([2H])[2H])C([2H])([2H])[2H])C)([H])[C@]3(C)CCC\2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : ≥ 50 mg/mL (122.95 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[2]. Ringe JD, Schacht E. et al. Prevention and therapy of osteoporosis: the roles of plain vitamin D and alfacalcidol. Rheumatol Int. 2004 Jul;24(4):189-97. [Content Brief]
[3]. Ivarsen P, Povlsen JV, Christensen KL.Effect of alfacalcidol on cardiac function in patients with chronic kidney disease stage 4 and secondary hyperparathyroidism: A pilot study.Scand J Urol Nephrol. 2012 Jun 25. [Content Brief]
[4]. Rianthavorn P,et al. Prevention of bone loss in children receiving long-term glucocorticoids with calcium and alfacalcidol or menatetrenone.J Pediatr Endocrinol Metab. 2012;25(3-4):307-12. [Content Brief]
[5]. Ringe JD, Farahmand P, Schacht E.Alfacalcidol in men with osteoporosis: a prospective, observational, 2-year trial on 214 patients.Rheumatol Int. 2012 Apr 8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4590 mL | 12.2950 mL | 24.5900 mL | 61.4749 mL |
| 5 mM | 0.4918 mL | 2.4590 mL | 4.9180 mL | 12.2950 mL | |
| 10 mM | 0.2459 mL | 1.2295 mL | 2.4590 mL | 6.1475 mL | |
| 15 mM | 0.1639 mL | 0.8197 mL | 1.6393 mL | 4.0983 mL | |
| 20 mM | 0.1229 mL | 0.6147 mL | 1.2295 mL | 3.0737 mL | |
| 25 mM | 0.0984 mL | 0.4918 mL | 0.9836 mL | 2.4590 mL | |
| 30 mM | 0.0820 mL | 0.4098 mL | 0.8197 mL | 2.0492 mL | |
| 40 mM | 0.0615 mL | 0.3074 mL | 0.6147 mL | 1.5369 mL | |
| 50 mM | 0.0492 mL | 0.2459 mL | 0.4918 mL | 1.2295 mL | |
| 60 mM | 0.0410 mL | 0.2049 mL | 0.4098 mL | 1.0246 mL | |
| 80 mM | 0.0307 mL | 0.1537 mL | 0.3074 mL | 0.7684 mL | |
| 100 mM | 0.0246 mL | 0.1229 mL | 0.2459 mL | 0.6147 mL |
Powered by Bioz