Furosine dihydrochloride
Based on 1 publication(s) in Google Scholar
Furosine dihydrochloride, an amino acid derivative, is an important chemical marker of early-stage Maillard reactions. Furosine dihydrochloride is closely related to a variety of diseases such as diabetes.
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- Pureza: 98.89%
- No. CAS: 157974-36-2
- Fòrmula: C12H20Cl2N2O4
- Peso molecular:327.20
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Almacenamiento:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Furosine dihydrochloride
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Actividad biológica
Descripciòn
In Vitro
Furosine could degrade slowly to form many different advanced glycation end products (AGEs). Partial AGEs have been proven to be closely related to a variety of diseases, such as diabetes, and a high amount of AGEs in human bodies is considered harmful[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 157974-36-2
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Appearance Solid
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Peso molecular 327.20
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Fòrmula C12H20Cl2N2O4
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Color Light yellow to brown
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SMILES
N[C@@H](CCCCNCC(C1=CC=CO1)=O)C(O)=O.[H]Cl.[H]Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvente y solubilidad
In Vitro:
H2O : 12.5 mg/mL (38.20 mM; Need ultrasonic)
DMSO : 4 mg/mL (12.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Li Y, et, al. Qualitative and quantitative analysis of furosine in fresh and processed ginsengs. J Ginseng Res. 2018 Jan;42(1):21-26. [Content Brief]
[2]. Poojary MM, et, al. Liquid chromatography quadrupole-Orbitrap mass spectrometry for the simultaneous analysis of advanced glycation end products and protein-derived cross-links in food and biological matrices. J Chromatogr A. 2020 Mar 29;1615:460767. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 3.0562 mL | 15.2812 mL | 30.5623 mL | 76.4059 mL |
| 5 mM | 0.6112 mL | 3.0562 mL | 6.1125 mL | 15.2812 mL | |
| 10 mM | 0.3056 mL | 1.5281 mL | 3.0562 mL | 7.6406 mL | |
| H2O | 15 mM | 0.2037 mL | 1.0187 mL | 2.0375 mL | 5.0937 mL |
| 20 mM | 0.1528 mL | 0.7641 mL | 1.5281 mL | 3.8203 mL | |
| 25 mM | 0.1222 mL | 0.6112 mL | 1.2225 mL | 3.0562 mL | |
| 30 mM | 0.1019 mL | 0.5094 mL | 1.0187 mL | 2.5469 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.