Galactosylhydroxylysine hydrochloride

Name: Galactosylhydroxylysine hydrochloride
Brand: MedChemExpress
SKU: HY-113230B
Rating: 4.5 (1 reviews)

Cat. No.: HY-113230B Purity: 99.69%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Galactosylhydroxylysine hydrochloride is a component of bone collagen produced by post-translational glycosylation of hydroxylysine. Galactosylhydroxylysine hydrochloride is released during bone resorption and has been shown to be elevated in metabolic bone loss.

For research use only. We do not sell to patients.

Galactosylhydroxylysine hydrochloride Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 480	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 1120	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 1800	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Galactosylhydroxylysine hydrochloride:

Galactosylhydroxylysine Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

360.79

Formula

C₁₂H₂₅ClN₂O₈

Appearance

Oil

Color

Light yellow to yellow

SMILES

N[C@@H](CCC(O[C@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)O)CN)C(O)=O.[H]Cl

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (277.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7717 mL	13.8585 mL	27.7170 mL
5 mM	0.5543 mL	2.7717 mL	5.5434 mL
10 mM	0.2772 mL	1.3858 mL	2.7717 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (6.93 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (6.93 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.87%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (248 KB) HNMR (147 KB) RP-HPLC (270 KB)

Handling Instructions (2659 KB)

References

[1]. Leigh SD, et al. Development of an immunoassay for urinary galactosylhydroxylysine. J Immunol Methods. 1998;220(1-2):169-178. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.7717 mL	13.8585 mL	27.7170 mL	69.2924 mL
	5 mM	0.5543 mL	2.7717 mL	5.5434 mL	13.8585 mL
	10 mM	0.2772 mL	1.3858 mL	2.7717 mL	6.9292 mL
	15 mM	0.1848 mL	0.9239 mL	1.8478 mL	4.6195 mL
	20 mM	0.1386 mL	0.6929 mL	1.3858 mL	3.4646 mL
	25 mM	0.1109 mL	0.5543 mL	1.1087 mL	2.7717 mL
	30 mM	0.0924 mL	0.4619 mL	0.9239 mL	2.3097 mL
	40 mM	0.0693 mL	0.3465 mL	0.6929 mL	1.7323 mL
	50 mM	0.0554 mL	0.2772 mL	0.5543 mL	1.3858 mL
	60 mM	0.0462 mL	0.2310 mL	0.4619 mL	1.1549 mL
	80 mM	0.0346 mL	0.1732 mL	0.3465 mL	0.8662 mL
	100 mM	0.0277 mL	0.1386 mL	0.2772 mL	0.6929 mL