IX 207-887
Based on 1 Customer Validation
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.96%
- No. CAS: 98320-39-9
- Fòrmula: C16H12O3S
- Peso molecular:284.33
-
Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
-
Solvente y solubilidad
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
IL-2 |
IL-1 |
In Vitro
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 98320-39-9
-
Appearance Solid
-
Peso molecular 284.33
-
Fòrmula C16H12O3S
-
Color Light yellow to yellow
-
SMILES
OC(/C=C1C2=C(SC=C2)C(OC)=CC3=C\1C=CC=C3)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (351.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
-
Ficha de datos (275 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5170 mL | 17.5852 mL | 35.1704 mL | 87.9260 mL |
| 5 mM | 0.7034 mL | 3.5170 mL | 7.0341 mL | 17.5852 mL | |
| 10 mM | 0.3517 mL | 1.7585 mL | 3.5170 mL | 8.7926 mL | |
| 15 mM | 0.2345 mL | 1.1723 mL | 2.3447 mL | 5.8617 mL | |
| 20 mM | 0.1759 mL | 0.8793 mL | 1.7585 mL | 4.3963 mL | |
| 25 mM | 0.1407 mL | 0.7034 mL | 1.4068 mL | 3.5170 mL | |
| 30 mM | 0.1172 mL | 0.5862 mL | 1.1723 mL | 2.9309 mL | |
| 40 mM | 0.0879 mL | 0.4396 mL | 0.8793 mL | 2.1982 mL | |
| 50 mM | 0.0703 mL | 0.3517 mL | 0.7034 mL | 1.7585 mL | |
| 60 mM | 0.0586 mL | 0.2931 mL | 0.5862 mL | 1.4654 mL | |
| 80 mM | 0.0440 mL | 0.2198 mL | 0.4396 mL | 1.0991 mL | |
| 100 mM | 0.0352 mL | 0.1759 mL | 0.3517 mL | 0.8793 mL |
IX 207-887 Related Classifications
HY-106087 Related Classifications
Powered by Bioz