ESR1 - estrogen receptor 1 Gene

Also Known as ER; ESR; Era; ESRA; ESTRR; NR3A1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 2099

About ESR1

Cytogenetic location: 6q25.1-q25.2 Genomic coordinates (GRCh38): 6:151,656,672-152,129,619 (from NCBI)

This gene has 14 transcripts (splice variants), 212 orthologues, 8 paralogues and is associated with 105 phenotypes. Biased expression in endometrium (RPKM 20.7), prostate (RPKM 2.1) and 3 other tissues.

Summary

This gene encodes an Estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with Estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and Other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast Cancer, endometrial Cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020]

ESR1 Products (45)

mRNA	Protein	Name
XM_017010379.2	XP_016865868.1	estrogen receptor isoform X1
NM_001385568.1	NP_001372497.1	estrogen receptor isoform 1
XM_047418292.1	XP_047274248.1	estrogen receptor isoform X2
XM_011535543.3	XP_011533845.1	estrogen receptor isoform X1
NM_001328100.2	NP_001315029.1	estrogen receptor isoform 4
XM_017010378.2	XP_016865867.1	estrogen receptor isoform X1
XM_047418298.1	XP_047274254.1	estrogen receptor isoform X4
NM_001385572.1	NP_001372501.1	estrogen receptor isoform 5
XM_047418290.1	XP_047274246.1	estrogen receptor isoform X1
XM_011535545.3	XP_011533847.1	estrogen receptor isoform X1
XM_017010377.2	XP_016865866.1	estrogen receptor isoform X1
NM_001122741.2	NP_001116213.1	estrogen receptor isoform 1
NM_001385571.1	NP_001372500.1	estrogen receptor isoform 5
NM_000125.4	NP_000116.2	estrogen receptor isoform 1
XM_047418293.1	XP_047274249.1	estrogen receptor isoform X2
XM_011535547.3	XP_011533849.1	estrogen receptor isoform X2
NM_001291241.2	NP_001278170.1	estrogen receptor isoform 3
XM_047418299.1	XP_047274255.1	estrogen receptor isoform X4
XM_047418296.1	XP_047274252.1	estrogen receptor isoform X3
XM_047418297.1	XP_047274253.1	estrogen receptor isoform X4
XM_047418291.1	XP_047274247.1	estrogen receptor isoform X2
XM_011535549.3	XP_011533851.1	estrogen receptor isoform X5
XM_047418294.1	XP_047274250.1	estrogen receptor isoform X2
XM_047418295.1	XP_047274251.1	estrogen receptor isoform X3
NM_001291230.2	NP_001278159.1	estrogen receptor isoform 2
NM_001122742.2	NP_001116214.1	estrogen receptor isoform 1
XM_017010381.2	XP_016865870.1	estrogen receptor isoform X1
NM_001385569.1	NP_001372498.1	estrogen receptor isoform 1
NM_001122740.2	NP_001116212.1	estrogen receptor isoform 1
XM_017010380.2	XP_016865869.1	estrogen receptor isoform X1
NM_001385570.1	NP_001372499.1	estrogen receptor isoform 5
XM_047418289.1	XP_047274245.1	estrogen receptor isoform X1
XM_017010383.2	XP_016865872.1	estrogen receptor isoform X6
NM_000125.4	NP_000116.2	estrogen receptor isoform 1
NM_001122740.2	NP_001116212.1	estrogen receptor isoform 1
NM_001122741.2	NP_001116213.1	estrogen receptor isoform 1
NM_001122742.2	NP_001116214.1	estrogen receptor isoform 1
NM_001291230.2	NP_001278159.1	estrogen receptor isoform 2
NM_001291241.2	NP_001278170.1	estrogen receptor isoform 3
NM_001328100.2	NP_001315029.1	estrogen receptor isoform 4
NM_001385568.1	NP_001372497.1	estrogen receptor isoform 1
NM_001385569.1	NP_001372498.1	estrogen receptor isoform 1
NM_001385570.1	NP_001372499.1	estrogen receptor isoform 5
NM_001385571.1	NP_001372500.1	estrogen receptor isoform 5
NM_001385572.1	NP_001372501.1	estrogen receptor isoform 5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Referencias	Source
enables 14-3-3 protein binding	IPI IPI: Inferred from physical interaction	21946067	GOA
enables ATPase binding	IDA IDA: Inferred from direct assay	12058073	GOA
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	12047722	GOA
enables G protein-coupled estrogen receptor activity	IMP IMP: Inferred from mutant phenotype	16645038	GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	12047722	GOA
enables TBP-class protein binding	IPI IPI: Inferred from physical interaction	11595744	GOA
enables TFIIB-class transcription factor binding	IPI IPI: Inferred from physical interaction	9841876	GOA
enables beta-catenin binding	IPI IPI: Inferred from physical interaction	15304487	GOA
enables calmodulin binding	EXP EXP: Inferred from Experiment	22275375	GOA
enables chromatin binding	IDA IDA: Inferred from direct assay	17505058	GOA
enables enzyme binding	IPI IPI: Inferred from physical interaction	12039952	GOA
enables estrogen response element binding	IDA IDA: Inferred from direct assay	9841876	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	11265755	GOA
enables nuclear estrogen receptor activity	IDA IDA: Inferred from direct assay	9841876	GOA
enables nuclear estrogen receptor binding	IPI IPI: Inferred from physical interaction	9841876	GOA
enables nuclear receptor activity	IDA IDA: Inferred from direct assay	9338790	GOA
enables nuclear receptor activity	IGI IGI: Inferred from genetic interaction	18722177	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	1517211	GOA
enables protein kinase binding	IPI IPI: Inferred from physical interaction	28068668	GOA
enables sequence-specific double-stranded DNA binding	IDA IDA: Inferred from direct assay	28473536	GOA
enables transcription coactivator binding	IPI IPI: Inferred from physical interaction	21642474	GOA
enables transcription coregulator binding	IPI IPI: Inferred from physical interaction	14701856	GOA
enables transcription corepressor binding	IPI IPI: Inferred from physical interaction	12535528	GOA

Biological Process GO Annotation	Evidence	Referencias	Source
involved in RNA polymerase II preinitiation complex assembly	IDA IDA: Inferred from direct assay	9841876	GOA
involved in cellular response to estradiol stimulus	IDA IDA: Inferred from direct assay	12535528	GOA
involved in estrogen receptor signaling pathway	IDA IDA: Inferred from direct assay	9338790	GOA
involved in negative regulation of DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	10816575	GOA
involved in negative regulation of canonical NF-kappaB signal transduction	IDA IDA: Inferred from direct assay	7651415	GOA
involved in negative regulation of gene expression	IDA IDA: Inferred from direct assay	21695196	GOA
involved in negative regulation of miRNA transcription	IMP IMP: Inferred from mutant phenotype	20388878	GOA
involved in negative regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	20388878	GOA
involved in positive regulation of DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	9328340	GOA
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	20074560	GOA
involved in positive regulation of nitric oxide biosynthetic process	IDA IDA: Inferred from direct assay	21937726	GOA
involved in positive regulation of nitric-oxide synthase activity	IDA IDA: Inferred from direct assay	21937726	GOA
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	11544182	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	9841876	GOA
involved in protein localization to chromatin	IMP IMP: Inferred from mutant phenotype	20388878	GOA
involved in response to estradiol	IDA IDA: Inferred from direct assay	15304487	GOA
involved in response to estrogen	IDA IDA: Inferred from direct assay	11581164	GOA
involved in steroid hormone receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	16645038	GOA

Cellular Component GO Annotation	Evidence	Referencias	Source
located in chromatin	IDA IDA: Inferred from direct assay	15831516	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	17505058	GOA
located in euchromatin	IDA IDA: Inferred from direct assay	17505058	GOA
located in nucleus	IDA IDA: Inferred from direct assay	9841876	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	15569929	GOA
is active in plasma membrane	IMP IMP: Inferred from mutant phenotype	16645038	GOA
part of protein-containing complex	IDA IDA: Inferred from direct assay	20080953	GOA
part of protein-containing complex	IMP IMP: Inferred from mutant phenotype	11595744	GOA
part of transcription regulator complex	IPI IPI: Inferred from physical interaction	11265755	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ESR1 Protein Structure

Oest_recep

zf-C4

Hormone_recep

ESR1_C

0
100
200
300
400
500
595 a.a.

Protein Preferred Names	Protein Names
estrogen receptor	E2 receptor alpha ER-alpha estradiol receptor estrogen nuclear receptor alpha estrogen receptor alpha E1-E2-1-2 estrogen receptor alpha E1-N2-E2-1-2 nuclear receptor subfamily 3 group A member 1 oestrogen receptor alpha

ESR1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Referencias
Intra	ESR1	P03372	BTF3	Homo sapiens	P20290-2	Anti Bait CoIP	18025262
Intra	ESR1	P03372	FOXO1	Homo sapiens	Q12778	Pull Down	11353774
Intra	ESR1	P03372	CUEDC2	Homo sapiens	Q9H467	Anti Tag CoIP	17347654
Intra	ESR1	P03372	PGR	Homo sapiens	P06401-1	Y2H	12612073
Intra	ESR1	P03372	PGR	Homo sapiens	P06401-1	Anti Bait CoIP	12612073
Intra	ESR1	P03372	PGR	Homo sapiens	P06401-1	Pull Down	12612073
Intra	ESR1	P03372	TRIM24	Homo sapiens	O15164	Pull Down	21182203
Intra	ESR1	P03372	PAGR1	Homo sapiens	Q9BTK6	Pull Down	19039327
Intra	ESR1	P03372	CITED1	Homo sapiens	Q99966	Pull Down	11581164
Intra	ESR1	P03372	CITED1	Homo sapiens	Q99966	Anti Tag CoIP	11581164
Intra	ESR1	P03372	ZNF366	Homo sapiens	Q8N895	Pull Down	17085477
Intra	ESR1	P03372	ZNF366	Homo sapiens	Q8N895	Y2H	17085477
Intra	ESR1	P03372	KDM6B	Homo sapiens	O15054	Anti Bait CoIP	21841772
Intra	ESR1	P03372	CCN2	Homo sapiens	P29279	Anti Tag CoIP	21629692
Intra	ESR1	P03372	CCN2	Homo sapiens	P29279	IF	21629692
Intra	ESR1	P03372	CCN2	Homo sapiens	P29279	Pull Down	21629692
Intra	ESR1	P03372	CCN2	Homo sapiens	P29279	Y2H	21629692
Intra	ESR1	P03372	CCN2	Homo sapiens	P29279	ELISA	21629692
Intra	ESR1	P03372	EGFR	Homo sapiens	P00533	Anti Bait CoIP	17284441
Intra	ESR1	P03372	MYL6	Homo sapiens	P60660	Density Sedimentation	21182205
Intra	ESR1	P03372	MYL6	Homo sapiens	P60660	Affinity Chrom	21182205
Intra	ESR1	P03372	MYL6	Homo sapiens	P60660	Phage Display	21217774
Intra	ESR1	P03372	NSD3	Homo sapiens	Q9BZ95	TAP	31527615
Intra	ESR1	P03372	NSD3	Homo sapiens	Q9BZ95	Y2H Array	25640309
Intra	ESR1	P03372	SP3	Homo sapiens	Q02447	TAP	31527615
Intra	ESR1	P03372	SP3	Homo sapiens	Q02447	Pull Down	10816575
Cross	ESR1	P03372	Ncor1	Mus musculus	Q60974	Gal4 VP16 Complement	12904255
Cross	ESR1	P03372	Ncor1	Mus musculus	Q60974	Pull Down	12904255
Intra	ESR1	P03372	BRCA1	Homo sapiens	P38398	TAP	31527615
Intra	ESR1	P03372	BRCA1	Homo sapiens	P38398	Anti Tag CoIP	15674350
Intra	ESR1	P03372	BRCA1	Homo sapiens	P38398	Anti Bait CoIP	15674350
Intra	ESR1	P03372	BRCA1	Homo sapiens	P38398	Pull Down	15674350
Intra	ESR1	P03372	BRCA1	Homo sapiens	P38398	CoIP	11244506
Intra	ESR1	P03372	SAFB2	Homo sapiens	Q14151	Anti Bait CoIP	12660241
Intra	ESR1	P03372	PPP1CC	Homo sapiens	P36873	TAP	31527615
Intra	ESR1	P03372	HAX1	Homo sapiens	O00165	Phage Display	21217774
Intra	ESR1	P03372	HAX1	Homo sapiens	O00165	Y2H	21217774
Intra	ESR1	P03372	UXT	Homo sapiens	Q9UBK9	Anti Tag CoIP	28106301
Intra	ESR1	P03372	PHB2	Homo sapiens	Q99623	Y2H	10359819
Intra	ESR1	P03372	BLCAP	Homo sapiens	P62952	Y2H	21217774
Intra	ESR1	P03372	NDRG2	Homo sapiens	Q9UN36	Phage Display	21217774
Intra	ESR1	P03372	NDRG2	Homo sapiens	Q9UN36	Y2H	21217774
Intra	ESR1	P03372	MED1	Homo sapiens	Q15648	TAP	31527615
Intra	ESR1	P03372	LATS1	Homo sapiens	O95835	Anti Bait CoIP	28068668
Intra	ESR1	P03372	NCOA1	Homo sapiens	Q15788	FRET	17627277
Intra	ESR1	P03372	NCOA1	Homo sapiens	Q15788	CH-IP	16282588
Intra	ESR1	P03372	NCOA1	Homo sapiens	Q15788	Pull Down	11682626
Intra	ESR1	P03372	MACROD1	Homo sapiens	Q9BQ69	Anti Bait CoIP	17914104
Intra	ESR1	P03372	MACROD1	Homo sapiens	Q9BQ69	Y2H	17914104
Intra	ESR1	P03372	GRIP1	Homo sapiens	Q9Y3R0	Pull Down	17932106
Intra	ESR1	P03372	SRC	Homo sapiens	P12931	Anti Bait CoIP	17043237
Intra	ESR1	P03372	SRC	Homo sapiens	P12931	PLA	23065768
Intra	ESR1	P03372	SRC	Homo sapiens	P12931	Anti Bait CoIP	17921256
Cross	ESR1	P03372	Pfn1	Mus musculus	P62962	IF	23576398
Intra	ESR1	P03372	ATAD2	Homo sapiens	Q6PL18	TAP	31527615
Intra	ESR1	P03372	ATAD2	Homo sapiens	Q6PL18	Y2H Array	25640309
Intra	ESR1	P03372	PPP5C	Homo sapiens	P53041	Anti Tag CoIP	14764652
Intra	ESR1	P03372	PPP5C	Homo sapiens	P53041	Y2H	14764652
Intra	ESR1	P03372	DNM1L	Homo sapiens	O00429	Y2H	21217774
Intra	ESR1	P03372	RELA	Homo sapiens	Q04206	Anti Bait CoIP	17932106
Intra	ESR1	P03372	RELA	Homo sapiens	Q04206	TAP	31527615
Intra	ESR1	P03372	RELA	Homo sapiens	Q04206	Pull Down	7651415
Intra	ESR1	P03372	DCAF13	Homo sapiens	Q9NV06	Anti Bait CoIP	28068668
Intra	ESR1	P03372	RBFOX2	Homo sapiens	O43251	Pull Down	11875103
Intra	ESR1	P03372	ASF1A	Homo sapiens	Q9Y294	TAP	31527615
Intra	ESR1	P03372	ASF1A	Homo sapiens	Q9Y294	Phage Display	21217774
Intra	ESR1	P03372	ASF1A	Homo sapiens	Q9Y294	Y2H	21217774
Cross	ESR1	P03372	Jun	Mus musculus	P05627	Y2H	11477071
Cross	ESR1	P03372	Jun	Mus musculus	P05627	Pull Down	11477071
Intra	ESR1	P03372	RAC3	Homo sapiens	P60763	Anti Bait CoIP	21217774
Intra	ESR1	P03372	EDF1	Homo sapiens	O60869	TAP	31527615
Intra	ESR1	P03372	PRMT2	Homo sapiens	P55345	IF	22093364
Intra	ESR1	P03372	PRMT2	Homo sapiens	P55345	Anti Tag CoIP	12039952
Intra	ESR1	P03372	PRMT2	Homo sapiens	P55345	Pull Down	12039952
Intra	ESR1	P03372	PRMT2	Homo sapiens	P55345	Pull Down	22093364
Intra	ESR1	P03372	PRMT2	Homo sapiens	P55345	Anti Tag CoIP	22093364
Intra	ESR1	P03372	PRMT2	Homo sapiens	P55345	Y2H	12039952
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	Density Sedimentation	21182205
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	TAP	31527615
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	Y2H	11265755
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	Y2H	11682626
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	Pull Down	11265755
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	Affinity Chrom	21182205
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	PLA	23065768
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	Pull Down	11682626
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	Transcription Compl	11265755
Intra	ESR1	P03372	ESR1	Homo sapiens	P03372	Pull Down	21182205
Intra	ESR1	P03372	PGR	Homo sapiens	P06401	Crosslink	26153859
Intra	ESR1	P03372	PGR	Homo sapiens	P06401	CH-IP	22396492
Intra	ESR1	P03372	PGR	Homo sapiens	P06401	Anti Bait CoIP	12612073
Intra	ESR1	P03372	NCOA3	Homo sapiens	Q9Y6Q9	Pull Down	11353774
Intra	ESR1	P03372	NCOA3	Homo sapiens	Q9Y6Q9	Crosslink	26153859
Intra	ESR1	P03372	NCOA3	Homo sapiens	Q9Y6Q9	Pull Down	21182203
Intra	ESR1	P03372	NCOA2	Homo sapiens	Q15596	Y2H	11265755
Intra	ESR1	P03372	NCOA2	Homo sapiens	Q15596	Pull Down	11265755
Intra	ESR1	P03372	NCOA2	Homo sapiens	Q15596	Transcription Compl	11265755
Intra	ESR1	P03372	CACUL1	Homo sapiens	Q86Y37	Pull Down	23178685
Intra	ESR1	P03372	ATF1	Homo sapiens	P18846	TAP	31527615
Intra	ESR1	P03372	TXNRD1	Homo sapiens	Q16881-4	Pull Down	15199063
Intra	ESR1	P03372	TXNRD1	Homo sapiens	Q16881-4	FRAP	15199063
Intra	ESR1	P03372	ARID5A	Homo sapiens	Q03989	Anti Tag CoIP	15941852
Intra	ESR1	P03372	CEBPB	Homo sapiens	P17676	TAP	31527615
Intra	ESR1	P03372	KMT2D	Homo sapiens	O14686	Pull Down	16603732
Cross	ESR1	P03372	SRC	Gallus gallus	P00523	Anti Bait CoIP	17921256
Cross	ESR1	P03372	SRC	Gallus gallus	P00523	Pull Down	11032808

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant ESR1 Proteins

Referencia número	Nombre del producto	Accession	Pureza
HY-P70248	ER alpha/ESR1 Protein, Human (His)	P03372-1 (M1-Q116)	≥ 90%, as determined by reducing SDS-PAGE.

ESR1 Antibodies

Referencia número	Nombre del producto	Aplicación	Reactivity
HY-P80662	Estrogen Receptor alpha Antibody (YA768)	WB	Human, Mouse, Rat
HY-P80662A	Estrogen Receptor alpha Antibody (YA768)(PBS only)	WB	Human, Mouse, Rat
HY-P80663	Estrogen Receptor alpha Antibody (YA450)	WB, IHC-F, IHC-P, ICC/IF, IP, ChIP	Human
HY-P80663A	Estrogen Receptor alpha Antibody (YA450)(PBS only)	WB, IHC-F, IHC-P, ICC/IF, IP, ChIP	Human
HY-P810664	Phospho-Estrogen Receptor alpha (Ser118) Antibody (YA9924)	WB, ICC/IF, IF-Tissue, IHC-P	Human, Mouse
HY-P83932	Estrogen Receptor alpha Antibody (YA3629)	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Rabbit
HY-P83932A	Estrogen Receptor alpha Antibody (YA3629)(PBS only)	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Rabbit
HY-P86246	Estrogen Receptor alpha Antibody (YA5938)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Postmenopausal Atrophic Vaginitis	Atrophic Vaginitis Senile Vaginitis Senile Atrophic Vaginitis Atrophy Of Vagina Vaginal Atrophy
Bartholin'S Gland Adenoma	Bartholin Gland Adenoma
Interval Angle-Closure Glaucoma	Intermittent Angle-Closure Glaucoma Angle-Closure Glaucoma, Subacute Prodromal Angle Closure Glaucoma
Thoracic Cancer	Thoracic Tumor Thorax Cancer Thorax Neoplasm Tumor Of Thorax Thoracic Neoplasms
Fasciitis
Beta-Thalassemia	Beta Thalassemia Cooley'S Anemia Mediterranean Anemia Beta Thalassemia Intermedia Erythroblastic Anemia Thalassemia, Hispanic Gamma-Delta-Beta Thalassemia Major Thalassemia Minor Beta-Plus-Thalassemia Thalassemia, Beta Beta Thalassemia Major Beta Thalassemia Minor Thalassemias, Beta- Microcytemia, Beta Type Thalassemia, Beta Type B-THAL Mediterranean Anaemia Beta Thalassaemia Syndrome Mediterranean Disease Beta Thalassaemia Disease
Her2-Receptor Negative Breast Cancer
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1
Breast Intraductal Proliferative Lesion	Intraductal Proliferative Lesion Intraductal Proliferative Lesion Of The Breast
Reproductive Organ Benign Neoplasm
Vaginal Discharge
Testicular Disease	Testicular Dysfunction Testicular Diseases Disorder Of Testis Testis Disorder Testicular Disorders
Spinal Polio
Pre-Malignant Neoplasm
Breast Malignant Phyllodes Tumor	Malignant Cystosarcoma Phyllodes Malignant Phyllodes Tumor Of Breast Malignant Phyllodes Tumour Of Breast Phyllodes Breast Tumor Phyllodes Tumor Of The Breast Breast Malignant Phyllodes Tumour Malignant Mammary Phyllodes Tumor Malignant Mammary Phyllodes Tumour Malignant Phyllodes Neoplasm Malignant Phyllodes Tumor Malignant Phyllodes Tumour Phyllodes Breast Neoplasm Phyllodes Breast Tumour Phyllodes Tumor, Malignant Cystosarcoma Phyllodes Cystosarcoma Phyllodes Of The Breast Phylloides Tumor Malignant Breast Phyllodes Tumor Breast Phyllodes Tumor Phyllodes Tumor Malignant Phyllodes Cystosarcoma Of Unspecified Site
Carpal Tunnel Syndrome	Cts Carpal Tunnel Syndrome, Familial Carpal Tunnel Syndrome 1 CTS1 Amyotrophy, Thenar, Of Carpal Origin Carpal Tunnel Median Neuropathy Cts - Carpal Tunnel Syndrome Median Nerve Entrapment Carpal Canal Carpal Tunnel Compression Neuropathy, Carpal Tunnel Distal Median Nerve Compression Distal Median Nerve Entrapment Entrapment Neuropathy, Carpal Tunnel Median Neuropathy, Carpal Tunnel Median Neuropathy Carpal Tunnel Thenar Amyotrophy Of Crapal Origin
Varicocele	Scrotal Varices Varicoceles Varicocele Of Scrotum Scrotal Varicocele
Female Stress Incontinence	Female Urinary Stress Incontinence Stress Incontinence - Female
Breast Papillary Carcinoma	Breast Solid Papillary Carcinoma Papillary Carcinoma Of Breast Papillary Carcinoma Of The Breast Solid Papillary Carcinoma Of The Breast
Ovarian Mesodermal Adenosarcoma	Ovarian Mullerian Adenosarcoma Ovarian Adenosarcoma
Intravascular Fasciitis	Intravascular Pseudosarcomatous Fasciitis
Thoracic Benign Neoplasm	Benign Neoplasm Of Thorax
Ischemic Bone Disease
Angiomyolipoma	Angiomyolipoma Of Kidney
Vagina Leiomyosarcoma	Leiomyosarcoma Of The Vagina Vaginal Leiomyosarcoma
Endometrial Hyperplasia
Mixed Cell Adenoma
Female Breast Cancer	Female Breast Carcinoma Carcinoma Of Female Breast Mammary Carcinoma Of Female Breast Malignant Neoplasm Of Female Breast
Trichorhinophalangeal Syndrome, Type I	Trichorhinophalangeal Dysplasia Type I TRPS1 Trichorhinophalangeal Syndrome Type I Trps I Trichorhinophalangeal Syndrome Type 1 Type I Trichorhinophalangeal Syndrome Giedion Syndrome Trp Syndrome Tricho-Rhino-Phalangeal Syndrome 1 Trichorhinophalangeal Syndrome, Type Iii
Leiomyoma, Uterine	Uterine Leiomyoma Uterine Fibroids Uterine Fibroid Plexiform Leiomyoma UL Leiomyoma Of Corpus Uteri Uterus Fibroma
Urethral Benign Neoplasm	Urethral Neoplasms Neoplasm Of Urethra Neoplasm. Urethra Urethral Neoplasm Urethral Carcinoma Malignant Neoplasm Of Urethra
Cervical Polyp	Cervix Adenomatous Polyp
Vaginal Cancer	Malignant Neoplasm Of Vagina Vaginal Neoplasms Malignant Tumor Of Vagina Malignant Vaginal Tumor Neoplasm Of Vagina Vagina Neoplasm Vaginal Tumor Vaginal Carcinoma Vaginal Malignant Epithelial Tumor Vaginal Neoplasm Malignant Vaginal Neoplasm Vagina Carcinoma Vaginal Neoplasia Cancer Of Vagina Malignant Tumour Of Vagina Carcinoma Of Vagina Primary Malignant Neoplasm Of Vagina Vagina Wall Cancer Vaginal Wall Cancer
Breast Ductal Carcinoma	Ductal Breast Carcinoma Duct Carcinoma Carcinoma, Ductal Mammary Ductal Carcinoma Ductal Carcinoma
Osteonecrosis	Bone Necrosis Avascular Necrosis Of Bone Aseptic Necrosis Necrosis Of Bone Nos Aseptic Osteonecrosis Aseptic Necrosis Of Bone, Site Unspecified Aseptic Or Avascular Bone Necrosis Aseptic Necrosis Of Bone Necrotic Bone Necrotizing Bone Spontaneous Osteonecrosis Osteoradionecrosis
Adenosarcoma	Mullerian Adenosarcoma
Inflammatory Breast Carcinoma	Inflammatory Breast Cancer Inflammatory Carcinoma Of Breast Mastitis Carcinomatosa Breast Cancer, Inflammatory Inflammatory Breast Neoplasms Inflammatory Adenocarcinoma Of Breast
Vulvar Syringoma
Sex Cord-Gonadal Stromal Tumor	Sex Cord Stromal Tumour Sex Cord-Gonadal Stromal Tumour Sex Cord-Stromal Neoplasm Specialized Gonadal Neoplasm Specialized Gonadal Tumor Specialized Gonadal Tumour Sex Cord-Gonadal Stromal Tumors Sex Cord-Stromal Tumor Malignant Testicular Sex Cord-Stromal Tumor Sex Cord Stromal Tumor Of Testis
Progesterone Resistance	Pseudocorpus Luteum Insufficiency
Osteogenic Sarcoma	Osteosarcoma OSRC Osteosarcoma, Somatic Neoplasms, Bone Tissue Bone Tissue Neoplasm Osteoid Sarcoma Skeletal Sarcoma Osteosarcoma Of Bone Bone Sarcoma
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Intracystic Papillary Adenoma	Intracystic Papilloma
Ovarian Cystadenocarcinoma	Cystadenocarcinoma Of Ovary Cystadenocarcinoma Of The Ovary
Ductal Carcinoma In Situ	Noninfiltrating Intraductal Carcinoma
Vaginitis	Infective Vaginitis Inflammation Of Vagina Colpitis Vaginal Inflammation Vaginitis Nos
Ovarian Disease	Ovarian Dysfunction Ovarian Diseases Ovarian Disorders Disorder Of Endocrine Ovary
Peritoneal Benign Neoplasm
Syndromic X-Linked Intellectual Disability Type 10	Hsd10 Deficiency, Atypical Type Hsd10 Disease, Atypical Type X-Linked Intellectual Disability-Choreoathetosis-Abnormal Behavior Syndrome Mrxs10 Mental Retardation, X-Linked, Syndromic 10
Postpartum Depression	Maternity Blues Postnatal Depression Depression, Postpartum Post-Partum Depression Depression Postpartum
Anxiety	Anxiety Disorder Anxiety Disorders Anxiety State Anxieties Anxiety Neurosis
Cryptorchidism, Unilateral Or Bilateral	Cryptorchidism Undescended Testicle Undescended Testis Cryptorchism Undescended Testicles CRYPTO Impaired Testicular Descent Cryptosporidiosis Retained Testis Unilateral Cryptorchidism Unilateral Undescended Testis Nondescent Unilateral Testicle Unilateral Cryptorchism Ectopic Testis, Unilateral Bilateral Cryptorchidism Bilateral Cryptorchism Bilateral Nondescent Testicle Bilateral Undescended Testes Bilateral Ectopic Testes
Oropharynx Cancer	Oropharyngeal Cancer Oropharyngeal Carcinoma Malignant Neoplasm Of Oropharynx Malignant Oropharyngeal Tumor Malignant Tumor Of Oropharynx Malignant Tumour Of Mesopharynx Oropharyngeal Cancer, Adult Cancer Of The Oropharynx
Kidney Disease	Renal Failure Kidney Failure Kidney Diseases Nephropathy Abnormality Of The Kidney Impaired Renal Function Disease Renal Anomaly Kidney Dysfunction Renal Disease Nephropathies Renal Failure Adverse Event Abnormal Renal Function
Cribriform Carcinoma	Ductal Carcinoma, Cribriform Type Carcinoma Cribriform Carcinoma, Cribriform
Polyp Of Corpus Uteri	Endometrial/Uterine Polyp Polyp Of Endometrium Polyp Of The Uterus Polyp, Uterus
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Micropapillomatosis Labialis
Angelman Syndrome	AS Happy Puppet Syndrome Happy Puppet Syndrome, Formerly Puppetlike Syndrome
Tonsil Cancer	Tonsillar Neoplasms Malignant Neoplasm Of Faucial Tonsil Malignant Neoplasm Of Palatine Tonsil Malignant Neoplasm Of Tonsil, Faucial Malignant Tonsillar Tumor Malignant Tumor Of Tonsil Tonsillar Carcinoma Malignant Neoplasm Tonsil
Estrogen-Receptor Positive Breast Cancer
Comedo Carcinoma	Comedocarcinoma High Grade Ductal Breast Carcinoma In Situ
Breast Lobular Carcinoma	Cancer, Breast, Lobular Lobular Breast Carcinoma
Estrogen Resistance	Estrogen Resistance Syndrome ESTRR Estrogen Insensitivity
Marfan Syndrome	MFS Mfs1 Marfan'S Syndrome Marfan Syndrome Type 1 Marfan Syndrome, Type I Mass Phenotype Contractural Arachnodactyly Mass Syndrome Octd Overlap Connective Tissue Disease Marfanoid Hypermobility Syndrome Marfan Disease
Gastrointestinal Stromal Tumor	GIST Gastrointestinal Stromal Tumors Gastrointestinal Stromal Sarcoma Gastrointestinal Stromal Tumor, Familial Gant Gastrointestinal Stromal Tumour Stromal Tumor Of Gastrointestinal Tract Stromal Tumour Of Gastrointestinal Tract Gastrointestinal Stromal Neoplasm Paraganglioma And Gastric Stromal Sarcoma Plexosarcoma
Vaginal Disease	Vaginal Diseases
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Bartholin'S Gland Benign Neoplasm	Bartholin Gland Neoplasm Tumor Of Bartholin'S Gland Bartholin'S Gland Carcinoma
Apocrine Adenocarcinoma	Apocrine Carcinoma Apocrine Gland Carcinoma Carcinoma Of The Apocrine Gland Carcinoma Of Apocrine Gland
Prolactinoma	Prolactin-Producing Pituitary Gland Adenoma Prolactin-Secreting Pituitary Adenoma Forbes-Albright Syndrome Lactotroph Adenoma Prl-Secreting Pituitary Adenoma Prloma Pituitary Lactotrophic Adenoma Familial Prolactinoma Pituitary Adenoma, Prolactin-Secreting Prolactinoma Of Pituitary Gland PSPA
Gynecomastia
Intracranial Meningioma	Meningioma
Sweat Gland Disease	Sweat Gland Diseases
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Insulin-Like Growth Factor I	Insulin-Like Growth Factor I Deficiency IGF1 DEFICIENCY Insulin-Like Growth Factor I, Resistance To Growth Retardation With Deafness And Mental Retardation Due To Igf1 Deficiency Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency Growth Delay Due To Insulin-Like Growth Factor I Resistance IGF1RES Igf-I Resistance Growth Retardation With Sensorineural Deafness And Mental Retardation Somatomedin, End-Organ Insensitivity To Somatomedin-C Somatomedin-C, Resistance To Insulin-Like Growth Factor 1 Resistance To Igf-1 Resistance Somatomedin End-Organ Insensitivity To Somatomedin-C Resistance To Growth Delay-Deafness-Intellectual Disability Syndrome Growth Delay-Hearing Loss-Intellectual Disability Syndrome Igf-1 Deficiency Primary Insulin-Like Growth Factor Deficiency Resistance To Igf-1 Insulin-Like Growth Factor 1 Resistance End-Organ Insensitivity To Somatomedin Igf1 Resistance Resistance To Insulin-Like Growth Factor I Resistance To Somatomedin-C Insulin-Like Growth Factor 1, Resistance To
Uterine Body Mixed Cancer	Malignant Mixed Tumor Of Corpus Uteri Malignant Mixed Tumor, Not Otherwise Specified
Scoliosis
Breast Metaplastic Carcinoma	Metaplastic Carcinoma Of The Breast Metaplastic Breast Carcinoma Metaplastic Carcinoma Of Breast Metaplastic Breast Cancer
Testicular Cancer	Testis Cancer Testicular Carcinoma Testicular Neoplasms Malignant Neoplasm Of Testis Childhood Neoplasm Of The Testis Neoplasm Of Testis Pediatric Testicular Neoplasm Testicular Tumor Testis Neoplasm Testicular Tumors Testicular Neoplasm Testicular Malignant Germ Cell Tumor Childhood Testicular Neoplasm Carcinoma Of The Testis Cancer Of Testis Malignant Neoplasm Of Testis, Nos Malignant Neoplasm Of Testis, Unspecified Malignant Tumour Of Testis Testicle Cancer Primary Malignant Neoplasm Of Testis
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Leiomyomatosis
Barre-Lieou Syndrome	Cervicocranial Syndrome Posterior Cervical Sympathetic Syndrome
Testicular Germ Cell Cancer	Germ Cell Tumor Of Testis Testicular Germ Cell Tumor Testicular Germ Cell Neoplasm Testicular Malignant Germ Cell Tumor
Lobular Neoplasia	Lobular Carcinoma In Situ Lobular Carcinoma In Situ Of Breast Lobular Intraepithelial Neoplasia Non-Infiltrating Lobular Carcinoma Noninfiltrating Lobular Carcinoma Unspecified Site Noninfiltrating Lobular Carcinoma Of Breast Lobular Carcinoma In Situ Unspecified Site
Prostatic Hypertrophy	Benign Prostatic Hypertrophy Prostatic Hyperplasia
Adult Cystic Nephroma	Multilocular Cystic Nephroma, Mixed Epithelial Stromal Tumour And Renal Epithelial Stromal Tumour
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Diabetes Mellitus, Non-Insulin-Dependent Type 2 Diabetes T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Infertility Due To Extratesticular Cause	Infertility Due To Extratesticular Causes
Fat Necrosis Of Breast	Breast Fat Necrosis Aseptic Fat Necrosis Of Breast Breast Necrosis Nos
Papillary Carcinoma	Carcinoma, Papillary Carcinoma Papillary
Mucinous Adenofibroma
Hypospadias	Hypospadias Familial Familial Hypospadias
Myoma	Muscle Benign Neoplasm Myomatous Neoplasm Neoplasms, Muscle Tissue Benign Neoplasm Of The Muscle Muscle Neoplasm Muscle Tissue Neoplasm Myomatous Tumor Neoplasm Of Muscle Muscle Neoplasms Myomas
Pheochromocytoma	Pheochromocytoma, Susceptibility To Phaeochromocytoma Adrenal Gland Chromaffin Paraganglioma Adrenal Gland Chromaffinoma Adrenal Gland Paraganglioma Adrenal Gland Pheochromocytoma Chromaffin Paraganglioma Of The Adrenal Gland Intraadrenal Paraganglioma PCC Chromaffin Cell Tumor Medullary Chromaffinoma Medullary Paraganglioma Pheochromoblastoma Pheochromocytomas Chromaffin Cell Neoplasm Pheochromocytoma, Malignant
Vulvar Leiomyoma
Short Syndrome	Short Stature, Hyperextensibility, Hernia, Ocular Depression, Rieger Anomaly, And Teething Delay Aarskog-Ose-Pande Syndrome Lipodystrophy, Partial, With Rieger Anomaly And Short Stature Lipodystrophy-Rieger Anomaly-Diabetes Syndrome Rieger Anomaly-Partial Lipodystrophy Syndrome Partial Lipodystrophy With Rieger Anomaly And Short Stature Short Stature, Hyperextensibility, Hernia, Ocular Depression, Rieger Anomaly And Teething Delay Growth Retardation-Rieger Anomaly Short Stature-Hyperextensibility-Rieger Anomaly-Teething Delay SHORTS
Migraine With Aura	Classic Migraine Migraine With Typical Aura Migraine Accompagnée Complicated Migraine Classical Migraine Acute Migraine With Aura
Benign Breast Phyllodes Tumor	Phyllodes Tumor Benign Cystosarcoma Phyllodes Benign Phyllodes Neoplasm Benign Phyllodes Neoplasm Of The Breast Cystosarcoma Phyllodes Phyllodes Neoplasm Phyllodes Tumor, Benign
Leydig Cell Tumor	Leydig Cell Neoplasm Tumor, Leydig Cell Leydig Cell Tumor, Benign
Pelvic Organ Prolapse	Rectal Prolapse Pelvic Organ Prolapse, Susceptibility To Pelvic Organ Prolapse, Susceptibility To, 1 Prolapse Of Vagina And Rectum Vaginal Prolapse Pelvic Organ Prolapse 1 Procidentia, Rectum Prolapse Of Rectal Mucosa Procidentia Of Rectum Rectal Mucosa Prolapse Rectum Prolapse Procidentia Rectum Rp - [Rectal Prolapse] Male Proctocele Male Rectocele Proctoptosis Female Genital Prolapse Female Prolapse Incompetence Of Pelvic Fundus Relaxation Of Perineum Deficiency Of Perineum
Papilloma	Papillomatosis
Uterine Sarcoma	Sarcoma Of The Uterus Uterine Corpus Sarcoma
Mixed Cell Type Cancer	Malignant Mixed Neoplasm Malignant Mixed Tumor Mixed Neoplasm Mixed Tumor, Malignant Malignant Mixed Cancer Mixed Tumor Malignant Mixed Tumor, Not Otherwise Specified Mixed Salivary Gland Tumor Mixed Tumor, Not Otherwise Specified
Schizophrenia	SCZD Schizophrenia With Or Without An Affective Disorder Schizophrenia 12 Schizophrenia, Susceptibility To Schizophrenia-1 Dementia Praecox Schizophrenia 1
Nipple Carcinoma
Hypertrophy Of Breast	Breasts Enlarged Large Breast Hypertrophy Of Breast Nos Hypertrophy Of Male Breast Hypertrophic Breast Excessive Development Of Breast Macromastia Mastoplastia
Benign Breast Adenomyoepithelioma	Benign Adenomyoepithelioma Of The Breast
Uterine Carcinosarcoma	Carcinosarcoma Of The Corpus Uteri Mixed Mullerian Sarcoma Of Uterus Malignant Mixed Müllerian Tumor Of The Corpus Uteri Malignant Mixed Müllerian Tumor Of Corpus Uteri Mixed Müllerian Cancer Of Corpus Uteri Malignant Mixed Mullerian Tumor Of The Corpus Uteri Mixed Mullerian Cancer Of Corpus Uteri Uterine Corpus Carcinosarcoma
Cervical Adenocarcinoma	Adenocarcinoma Cervix Uteri Adenocarcinoma Of Cervix Adenocarcinoma Of The Uterine Cervix Adenocarcinoma Of The Cervix Uteri
Hypogonadotropic Hypogonadism	Klinefelter Syndrome Klinefelter'S Syndrome Xxy Syndrome Xxy Trisomy Hypogonadotropism 47, Xxy Congenital Idiopathic Hypogonadotropic Hypogonadism Isolated Congenital Gonadotropin Deficiency 47,Xxy Syndrome 47, Xxy Syndrome Klinefelters Syndrome Hypogonadism Klinefelter Syndrome In Males Klinefelter Syndrome, Unspecified Klinefelter Syndrome Karyotype 47, Xxy
Gender Incongruence	Gender Dysphoria Transsexualism Gender Identify Disorder
Glucose Intolerance	Glucose: Intolerance Glucose: Malabsorption Malabsorption Of Glucose Impaired Glucose Tolerance
In Situ Carcinoma	Carcinoma In Situ
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Leukemia, Myeloid, Acute Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Malignant Cystic Nephroma	Malignant Multilocular Cystic Nephroma Cystic Partially Differentiated Nephroblastoma
Lymphangioleiomyomatosis	Lymphangiomyomatosis LAM Lung Lymphangioleiomyomatosis Pulmonary Lymphangioleiomyomatosis Lymphangioleiomyomatosis, Somatic Lymphangio-Myomatosis
Autosomal Recessive Disease	Autosomal Recessive Disorder
Trigeminal Neuralgia	Tic Douloureux Trifacial Neuralgia Trifocal Neuralgia Neuralgia Of The Fifth Cranial Nerve Neuralgia Of 5th Cranial Nerve Infraorbital Neuralgia
Breast Squamous Cell Carcinoma	Breast Primary Squamous Cell Carcinoma Primary Squamous Cell Carcinoma Of Breast Primary Squamous Cell Carcinoma Of The Breast Scc Of Breast Squamous Cell Carcinoma Of Breast Squamous Cell Breast Carcinoma
Li-Fraumeni Syndrome	Sarcoma Family Syndrome Of Li And Fraumeni Sbla Syndrome LFS Li-Fraumeni Familiar Cancer Susceptibility Syndrome Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome Lfs1 Li Fraumeni Syndrome Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome Lfl Sbla Syndrome Li-Fraumeni-Like Syndrome Li-Fraumeni Syndrome 1
Breast Leiomyosarcoma	Leiomyosarcoma Of The Breast
Endometrial Disease	Endometrial Disorder Endometrial Diseases
Cardiovascular System Disease	Abnormality Of The Cardiovascular System Disease Of Subdivision Of Hemolymphoid System Disorder Of Cardiovascular System Cardiovascular Diseases Cardiovascular Disease
Teratoma	Teratomas
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Obesity , Susceptibility To Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Breast Mucinous Cystadenocarcinoma
Endometrial Adenocarcinoma	Endometrial Endometrioid Adenocarcinoma Endometrial Adenoacanthoma Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation Adenocarcinoma Of Endometrium Adenocarcinoma Of The Endometrium Adenocarcinoma Of Uterus Endometrial Endometrioid Adenocarcinoma With Squamous Differentiation Endometrioid Adenoma Or Carcinoma Endometrioid Adenomas And Carcinomas Endometrioid Carcinoma Of Endometrium Endometrium Adenocarcinoma
Mammary Paget'S Disease	Paget'S Disease Mammary Paget Disease Paget'S Disease Of The Breast Paget Disease Of The Breast Paget'S Disease Of The Nipple Paget'S Disease, Mammary Paget Cell Neoplasm Paget Disease Of The Nipple Pagets Disease Mammary Osteitis Deformans
Fallopian Tube Serous Adenocarcinoma
Bone Resorption Disease	Bone Resorption
Apocrine Sweat Gland Neoplasm	Apocrine Tumor Apocrine Neoplasm
Uterine Corpus Cancer	Corpus Uteri Cancer Malignant Uterine Corpus Neoplasm
Breast Fibroadenosis	Fibroadenosis Of Breast Fibroadenosis - Breast Adenofibrosis Of Breast Fibroadenosis Of Breast Nos
Smooth Muscle Tumor
Prostate Stromal Sarcoma	Stromal Sarcoma Of The Prostate
Amelogenesis Imperfecta	Ai Congenital Enamel Hypoplasia Al - [Amelogenesis Imperfecta]
Granulomatous Endometritis
Sporadic Breast Cancer	Sporadic Breast Carcinoma
Autism	Autistic Disorder Autism Susceptibility 1 Childhood Autism Autistic Disorder Of Childhood Onset Infantile Autism Kanner'S Syndrome Autistic
Colonic Benign Neoplasm	Colon Neoplasm Colonic Mass Colonic Tumor Neoplasm Of Colon Neoplasm Of The Colon Colonic Neoplasms Colon Cancer Colon Carcinoma Nos Colonic Cancer Metastatic Colon Cancer Nos
Intravenous Leiomyomatosis	Leiomyomatosis
Leukorrhea	Discharge - Leukorrhea Leukorrhea Of Vagina
Gynatresia
Autism Spectrum Disorder	Asd Autism Spectrum Disorders Autistic Continuum Pervasive Developmental Disorder Pervasive Development Disorder Autistic Behavior Autistic Disorder Autistic Autistic Disorder Of Childhood Onset Infantile Autism Childhood Autism Kanner Syndrome Pervasive Developmental Delay Nos Pervasive Developmental Disorder, Not Otherwise Specified
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Uterine Anomalies	Uterine Diseases Uterine Disease Uterine Abnormality
Bone Remodeling Disease
Lynch Syndrome	Hereditary Nonpolyposis Colon Cancer Hereditary Nonpolyposis Colorectal Cancer Hereditary Nonpolyposis Colorectal Carcinoma Hereditary Nonpolyposis Colorectal Neoplasms Familial Nonpolyposis Colon Cancer Hnpcc Coca 1 Hereditary Defective Mismatch Repair Syndrome Hereditary Non-Polyposis Colon Cancer Hereditary Non-Polyposis Colon Cancer Syndrome Hereditary Non-Polyposis Colorectal Cancer Hereditary Non-Polyposis Colorectal Cancer Syndrome Hereditary Nonpolyposis Colon Cancer Syndrome Hereditary Nonpolyposis Colorectal Cancer Syndrome Hereditary Nonpolyposis Colorectal Neoplasm Hnpcc - Hereditary Nonpolyposis Colon Cancer Cancer Family Syndrome Familial Nonpolyposis Colorectal Cancer Colon Cancer, Familial Nonpolyposis Colorectal Neoplasms, Hereditary Nonpolyposis Cancer, Colorectal, Nonpolyposis, Hereditary Colorectal Cancer, Hereditary Nonpolyposis, Type 1
Syringoma	Syringomas
Cowden Syndrome	Cowden Disease Multiple Hamartoma Syndrome Cowden'S Disease Lhermitte-Duclos Disease Cd Cs Mham Dysplastic Gangliocytoma Of Cerebellum Cowden'S Syndrome Hamartoma Syndrome, Multiple
Teeth Hard Tissue Disease
Hereditary Breast Ovarian Cancer Syndrome	Hereditary Breast And Ovarian Cancer Syndrome Brca1- And Brca2-Associated Hereditary Breast And Ovarian Cancer Breast And/Or Ovarian Cancer Breast And Ovarian Cancer Syndrome Hboc Syndrome Hereditary Breast And Ovarian Cancer Brca1- Brca2-Associated Hboc
Breast Fibroadenoma	Fibroadenoma Fibroadenoma Of Breast Juvenile Fibroadenoma Of Breast Cellular Fibroadenoma Complex Fibroadenoma Of Breast Juvenile Fibroadenoma Fibroadenoma Nos Fibroadenoma Unspecified Site
Skin Disease	Skin Diseases Abnormality Of The Skin Skin Diseases, Genetic Genodermatosis Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Aromatase Excess Syndrome	AEXS Increased Aromatase Activity Familial Hyperestrogenism Hereditary Prepubertal Gynecomastia Aromatase Activity, Increased Familial Gynecomastia Due To Increased Aromatase Activity Hereditary Gynecomastia Gynecomastia, Familial Familial Gynecomastia
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
46,Xy Sex Reversal	Swyer Syndrome Pure Gonadal Dysgenesis 46,Xy Gonadal Dysgenesis, Xy Female Type Gonadal Dysgenesis, 46,Xy 46,Xy Cgd 46,Xy Complete Gonadal Dysgenesis 46,Xy Pure Gonadal Dysgenesis 46 Xy Gonadal Dysgenesis 46, Xy Cgd 46, Xy Complete Gonadal Dysgenesis 46, Xy Pure Gonadal Dysgenesis Xy Pure Gonadal Dysgenesis Female With 46,Xy Karyotype Xy Females
Bilateral Breast Cancer	Bilateral Breast Carcinoma
Disorder Of Sexual Development	Disorder Of Sex Development Sex Development Disorder Sex Differentiation Disease Dsd Disorders Of Sex Development Sex Differentiation Disorders
Premature Menopause	Primary Ovarian Insufficiency Premature Ovarian Failure Hypergonadotropic Hypogonadism Premature Ovarian Insufficiency Menopause - Premature Menopause Praecox Menopause Premature Menopause, Premature Female Hypergonadotropic Hypogonadism Hypergonadotrophic Ovarian Failure Primary Female Hypogonadism Pof - [Premature Ovarian Failure] Ovarian Failure Ovarian Secretion Suppression Ovary Hyposecretion Ovary Secretion Deficiency Premature Menopause Nos
Cervical Adenosarcoma	Cervical Muellerian Adenosarcoma Cervical Mullerian Adenosarcoma
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Diffuse Peritoneal Leiomyomatosis	Disseminated Peritoneal Leiomyomatosis Leiomyomatosis Peritonealis Disseminata Dpl Lpd Leiomyomatosis Peritonealis Disseminate
Adenomyosis	Endometriosis Of Uterus Endometriosis Interna Endometriosis Of Myometrium Endometriosis, Myometrium Uterine Adenomyosis Adenomyosis Uteri Internal Endometriosis
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Asperger Syndrome	Asperger Disorder
Synchronous Bilateral Breast Carcinoma
Breast Adenoid Cystic Carcinoma	Adenoid Cystic Breast Carcinoma Adenoid Cystic Carcinoma Of Breast Mammary Adenocystic Carcinoma
Vulvar Benign Neoplasm
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Cancer Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Acute Promyelocytic Leukemia	Leukemia, Acute Promyelocytic Acute Myeloblastic Leukemia Type 3 Aml M3 APL Leukemia, Acute Promyelocytic, Somatic Aml With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Apml Acute Myeloblastic Leukemia 3 Acute Myeloid Leukemia With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Acute Myeloblastic Leukaemia Type 3 Acute Myeloid Leukaemia M3 Acute Myeloid Leukemia M3 Acute Promyelocytic Leukaemia M3 Anll Myeloid Leukemia, Acute, M3 Leukemia Promyelocytic Acute Leukemia, Promyelocytic, Acute Leukemia, Acute, Promyelocytic
Vagina Sarcoma	Sarcoma Of The Vagina Vaginal Sarcoma
Chronic Kidney Disease	Chronic Renal Disease Chronic Kidney Failure Ckd Chronic Renal Failure Kidney Failure, Chronic Chronic Renal Failure Syndrome Crf Renal Failure - Chronic Renal Failure Chronic Chronic Kidney Diseases Chronic Kidney Disease Stage 5 Ckd - [Chronic Kidney Disease] Crf - [Chronic Renal Failure] Chronic Kidney Impairment Chronic Renal Impairment Chronic Kidney Shutdown Chronic Hypoxic Kidney Failure Chronic Kidney Collapse Chronic Renal Insufficiency Chronic Kidney Toxaemia Chronic Kidney Hypofunction Chronic Renal Suppression Chronic Renal Failure, Stage 5 Ckd - [Chronic Kidney Disease] Stage 5 End Stage Kidney Failure End Stage Renal Failure End Stage Kidney Disease End Stage Renal Disease End Stage Chronic Renal Failure Esrf - [End Stage Renal Failure] Esrd - [End Stage Renal Diseases] Egfr - [Estimated Glomerular Filtration Rate] < 15 Ml/Min/1.73m²
Progesterone-Receptor Positive Breast Cancer
Estrogen-Receptor Negative Breast Cancer
Ovarian Seromucinous Carcinoma	Mixed Epithelial Carcinoma Of Ovary Ovary Mixed Epithelial Carcinoma
Adult Syndrome	Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome Acro Dermato Ungual Lacrimal Tooth Syndrome Pigment Anomaly-Ectrodactyly-Hypodontia Syndrome Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome Adult
Uterine Benign Neoplasm
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Breast Benign Neoplasm	Benign Tumour Of Breast Benign Neoplasm Of Female Breast
Wilms Tumor 1	Nephroblastoma Wilms Tumor WT1 Wilms' Tumor Bilateral Wilms Tumor Wilms Tumor, Type 1 Wilms Tumor, Somatic Adult Nephroblastoma Wt1 Disorder Renal Embryonic Tumor Adult Kidney Wilms Tumor Childhood Kidney Wilms Tumor Nonanaplastic Kidney Wilms Tumor
Rhabdomyosarcoma
Intraductal Papilloma	Papilloma, Intraductal Ductal Papilloma Papilloma Intraductal
Endometriosis Of Ovary	Ovarian Endometriosis
Liver Leiomyoma	Leiomyoma Of The Liver
Endocervical Carcinoma	Carcinoma Of Endocervix Carcinoma Of The Endocervix
Oncocytic Breast Carcinoma
Sweat Gland Cancer	Sweat Gland Carcinoma Malignant Neoplasm Of Sweat Gland Malignant Tumor Of The Sweat Gland Carcinoma Of The Sweat Gland Primary Malignant Neoplasm Of Sweat Gland Sweat Gland Neoplasms
Hemangioma	Hemangiomas
Migraine With Or Without Aura 1	Migraine Migraine With Or Without Aura, Susceptibility To, 1 Migraine Disorder Migraine Variant Migraines Migraine Disorders Mgr1 Mgau Ma Migraine With Or Without Aura Classic Migraine Common Migraine Disorder, Migraine Headache Migraine Headache Migrainous Migraine Headache Migraine Syndrome Headache Including Migraine Migraine, Susceptibility To
Glucocorticoid-Induced Osteoporosis	Steroid-Induced Osteoporosis
Ovary Adenocarcinoma	Ovarian Adenocarcinoma Adenocarcinoma Of The Ovary Ovarian Adenoacanthoma Adenocarcinoma Of Ovary
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Bipolar Disorder	Bipolar Depression Manic Disorder Depression, Bipolar Bipolar Disorder Manic Phase Depressive-Manic Psych. Manic Bipolar Affective Disorder Manic Bipolar I Disorder Manic Depression Manic Depressive Disorder Mixed Bipolar Disorder Bipolar Affective Disorder Bipolar Affective Psychosis Bipolar Spectrum Disorder Manic Depressive Illness Depression Bipolar Bipolar Disorder, Mixed Major Affective Disorder Major Affective Disorder 1 Major Affective Disorder 2
Microglandular Adenosis	Breast Fibrocystic Disease Adenosis - Breast Adenosis Of The Breast Fibrocystic Breast Disease Breast Adenosis Adenosis Of Breast
Tubular Adenocarcinoma	Tubular Carcinoma Adenocarcinoma Tubular Adenocarcinoma, Tubular
Serous Cystadenocarcinoma	Serous Adenocarcinoma Cystadenocarcinoma, Serous Serous Carcinoma Cystadenocarcinoma Serous
Autosomal Genetic Disease	Autosomal Hereditary Disorder
Arthrogryposis Multiplex Congenita 3, Myogenic Type	Arthrogryposis Multiplex Congenita, Myogenic Type AMC3 Amcm Autosomal Recessive Myogenic Arthrogryposis Multiplex Congenita Autosomal Recessive Myogenic Amc Syne1-Related Amc Syne1-Related Arthrogryposis Multiplex Congenita
Breast Carcinoma In Situ	Carcinoma In Situ Of Breast Non-Infiltrating Carcinoma Of Breast Breast Cancer In Situ
Adenomyoma
Leiomyosarcoma	Leiomyosarcomas
Diabetes Mellitus	Diabetes
Intraductal Breast Benign Neoplasm
Bizarre Leiomyoma	Atypical Leiomyoma Pleomorphic Leiomyoma Symplastic Leiomyoma
Infertility
Seminoma	Seminoma, Pure
Nonmucinous Bronchioloalveolar Adenocarcinoma
Meningioma, Familial	Meningioma Familial Meningioma Meningioma, Familial, Susceptibility To Meningeal Neoplasm Meningeal Neoplasms Meningiomas Meningioma, Nf2-Related, Somatic Meningioma, Sis-Related Meningothelial Cell Tumor Neoplasm Of The Meninges Primary Meningeal Tumor Familial Multiple Meningioma MNGMA Meningioma, Benign, No Icd-O Subtype Intracranial Meningioma Meningothelial Cell Neoplasm Supratentorial Meningioma Primary Neoplasm Of Spinal Meninges Benign Intracranial Meningioma Benign Meningioma Meningeal Tumours Meningeal Sarcoma Of Unspecified Site Meningothelial Sarcoma Of Unspecified Site
Hydrocele	Testicular Hydrocele
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Breast Adenocarcinoma	Mammary Adenocarcinoma Adenocarcinoma Of Breast
Varicose Veins	Varices Varix Venous Ectasia Venous Varices Varicosity
Breast Sarcoma	Sarcoma Of Breast
Spondylolisthesis	Slipped Vertebrae Acquired Spondylolisthesis
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Breast Disease	Breast Diseases
Amelogenesis Imperfecta, Type Ig	Enamel-Renal Syndrome Ers Amelogenesis Imperfecta Type 1g AI1G Enamel-Renal-Gingival Syndrome Amelogenesis Imperfecta And Gingival Fibromatosis Syndrome Aigfs Amelogenesis Imperfecta, Hypoplastic, With Nephrocalcinosis Amelogenesis Imperfecta Hypoplastic With Nephrocalcinosis Amelogenesis Imperfecta Type Ig Amelogenesis Imperfecta-Nephrocalcinosis Syndrome Amelogenesis Imperfecta 1g Hypoplastic Amelogenesis Imperfecta With Nephrocalcinosis Amelogenesis Imperfecta Nephrocalcinosis
Adhesions Of Uterus	Intrauterine Adhesions Intrauterine Synechiae Band Of Uterus Asherman Syndrome Internal Adhesion Of Uterus Internal Band Of Uterus
Desmoid Tumor	Aggressive Fibromatosis Desmoid Type Fibromatosis Familial Infiltrative Fibromatosis Desmoid Disorder, Hereditary Fif Fibromatosis, Familial Infiltrative Deep Fibromatosis Desmoid Fibromatosis Hereditary Desmoid Disease Musculoaponeurotic Fibromatosis Desmoid-Type Fibromatosis Fibromatosis, Aggressive Desmoid Disease, Hereditary Musculo-Aponeurotic Fibromatosis
Migraine Without Aura	Common Migraine Migraine With Or Without Aura, Susceptibility To Migraine Without Aura, Susceptibility To Acute Migraine Without Aura
Glycogen-Rich Clear Cell Breast Carcinoma	Glycogen-Rich Carcinoma
Vulvar Squamous Papilloma	Vestibular Papilloma
Breast Cystic Hypersecretory Carcinoma	Cystic Hypersecretory Carcinoma Of The Breast Cystic Hypersecretory Duct Carcinoma Of The Breast
Uterine Corpus Adenosarcoma	Adenosarcoma Of Uterine Corpus Uterine Corpus Mullerian Adenosarcoma
Endosalpingiosis
Endometrial Stromal Tumor	Endometrial Stromal Neoplasm Endometrial Stromal Tumors
Estrogen Excess	Hyperestrogenism
Ovarian Cyst	Ovarian Cysts
Dyslexia
Major Depressive Disorder	Seasonal Affective Disorder Unipolar Depression Depression MDD Depressive Disorder Unipolar Depression, Susceptibility To Major Depressive Disorder 1 Major Depressive Disorder, Response To Citalopram Therapy In Major Depressive Disorder 2 Winter Depression Single Major Depressive Episode Sad Clinical Depression Major Depression Depressive Syndrome Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment Seasonal Affective Disorder, Susceptibility To Recurrent Major Depression Affective Disorder, Seasonal Depression In A Seasonal Pattern Depression Seasonal Major Depressive Disorder With A Seasonal Pattern Seasonal Depression Seasonal Mood Disorder Mental Depression Recurrent Major Depressive Episodes
Vestibular Gland Benign Neoplasm
Endometrial Stromal Sarcoma	Ess Endometrial Stromal Sarcoma, High Grade Undifferentiated Endometrial Sarcoma Stromal Sarcoma Of The Corpus Uteri Sarcoma Endometrial Stromal Sarcoma, Endometrial Stromal Undifferentiated Stromal Sarcoma
Vulvar Leiomyosarcoma
Endometriosis	Endometriosis, Site Unspecified Endometrial Ectopia
Breast Myofibroblastoma
Bulbospinal Polio
Lipid-Rich Carcinoma
Cataract	Cataracts Cat - [Cataract] Cataract Form Lens Opacity Lens Opacities
Progesterone-Receptor Negative Breast Cancer
Atrophic Vulva	Atrophy Of Vulva
Rectum Carcinoma In Situ	Carcinoma In Situ Of Rectum Severe Dysplasia Of Rectum Severe Rectal Dysplasia Rectal Carcinoma In Situ Intraepithelial Neoplasia Of Rectum, High Grade
Malignant Ovarian Surface Epithelial-Stromal Neoplasm	Malignant Ovarian Surface Epithelial-Stromal Tumor
Endocervical Adenocarcinoma	Endocervical Carcinoma
Papillary Serous Adenocarcinoma	Micropapillary Serous Carcinoma Serous Surface Papillary Carcinoma Papillary Serous Carcinoma Papillary Serous Cystadenocarcinoma
Cervix Carcinoma	Cancer Of Cervix Carcinoma Of Cervix Carcinoma Cervix Uteri Carcinoma Of The Cervix Uteri
Gastric Diffuse Adenocarcinoma	Diffuse Gastric Adenocarcinoma Carcinoma, Diffuse Type
Female Reproductive Endometrioid Cancer	Endometrioid Tumor Endometrioid Neoplasm Female Reproductive Endometrioid Neoplasm
Leiomyoma	Leiomyomatous Neoplasm Leiomyomatous Tumor Leiomyomas Fibroid Tumor Uterine Fibroids

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)

Referencia número	Nombre del producto	Efecto	Pureza	Phase
HY-136255	Camizestrant	Inhibitor	99.32%	Phase 3

Pre-clinical Phase

Bioactive Molecules (14)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-147165	VT02956	Inhibitor	99.58%	Unkown
HY-21191	Perfluorobutanesulfonic acid		98.0%	Unkown
HY-N1508	Ecliptasaponin A		99.81%	Unkown
HY-163650	DTPD-Q		99.68%	Unkown
HY-149480	ERD-3111	Degrader	98.72%	Unkown
HY-RS04529	ESR1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS04530	Esr1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-101119	GLL398	Degrader	/	Unkown
HY-147165A	VT02956 hydrochloride	Inhibitor	/	Unkown
HY-183319	Anticancer agent 320		/	Unkown
HY-183804	PROTAC ER Degrader-16	Degrader	/	Unkown
HY-N17632	Moracin G		/	Unkown
HY-N18209	4-Hydroxy-3-butylphthalide		/	Unkown
HY-RS04531	Esr1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ESR1	MGD	MGI:1352467
Rattus norvegicus	ESR1	RGD	RGD:2581
Canis familiaris	ESR1	VGNC	VGNC:40476
Felis catus	ESR1	VGNC	VGNC:102420
Bos taurus	ESR1	VGNC	VGNC:53791
Macaca mulatta	ESR1	VGNC	VGNC:72432
Others	ESR1	NCBI