S1PR5 - sphingosine-1-phosphate receptor 5 Gene

Also Known as EDG8; S1P5

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100141401

About S1PR5

Primary_assembly 2: 69,293,546-69,298,377 reverse strand.Sscrofa11.1:CM000813.5

This gene has 2 transcripts (splice variants), 236 orthologues and 20 paralogues. Broad expression in spleen (RPKM 5.5), lung (RPKM 2.9) and 8 other tissues.

S1PR5 Products (2)

mRNA Protein Name
NM_001123109.1 NP_001116581.1 sphingosine 1-phosphate receptor 5
NM_001123109.1 NP_001116581.1 sphingosine 1-phosphate receptor 5

S1PR5 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (58 - 338)

7tm_GPCRs

7tm_GPCRs: cd14964 (60 - 84)

7tm_GPCRs

7tm_GPCRs: cd14964 (93 - 114)

7tm_GPCRs

7tm_GPCRs: cd14964 (130 - 152)

7tm_GPCRs

7tm_GPCRs: cd14964 (174 - 190)

7tm_GPCRs

7tm_GPCRs: cd14964 (211 - 234)

7tm_GPCRs

7tm_GPCRs: cd14964 (271 - 293)

7tm_GPCRs

7tm_GPCRs: cd14964 (306 - 331)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 420 a.a.
Protein Preferred Names Protein Names

sphingosine 1-phosphate receptor 5

  • S1P receptor 5

  • S1P receptor Edg-8

  • Sphingosine 1-phosphate receptor Edg-8

  • endothelial differentiation G-protein-coupled receptor 8

  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 8

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12355 Siponimod Agonist 99.95% Yes
HY-12288 Ozanimod Agonist 99.98% Yes
HY-10569 Ponesimod Agonist 99.78% Yes
HY-12288A Ozanimod hydrochloride Modulator 98.10% Yes
HY-12355A Siponimod hemifumarate Agonist 99.64% Yes

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-17606 Cenerimod Agonist 99.43% Phase 3

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111253 CYM-5478 Agonist 99.90% Unkown
HY-136578 RP101988 Agonist 98.80% Unkown
HY-176533 S1PR5-IN-1 Inhibitor 99.58% Unkown
HY-136576 RP101075 Agonist 99.19% Unkown
HY-148115 S1p receptor agonist 2 Agonist / Unkown
HY-148198 S1P5 receptor agonist-1 Agonist / Unkown
HY-136577 RP101442 Agonist / Unkown
HY-14402 AMG 369 Agonist / Unkown
HY-181875 S1PR1/S1PR5 agonist-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S1PR5 NCBI NCBI:53637