DEFB4B - defensin beta 4B Gene
Also Known as DEFB4P
Species: Homo sapiens
About DEFB4B
This gene has 1 transcript (splice variant), 1 gene allele, 8 orthologues and 3 paralogues. Biased expression in gall bladder (RPKM 1.0), esophagus (RPKM 0.7) and 3 other tissues.
Summary
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an Antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014]
DEFB4B Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001205266.2 | NP_001192195.1 | beta-defensin 4B precursor |
DEFB4B Protein Structure
Defensin_beta: Beta defensin (27 - 62)
- 0
- 64 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
beta-defensin 4B |
|
DEFB4B Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
DEFB4A | O15263 | ZMPSTE24 | Homo sapiens | O75844 | 33961781 | |
|
Intra
|
DEFB4A | O15263 | ZMPSTE24 | Homo sapiens | O75844 | 28514442 |
Recombinant DEFB4B Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P7135 | BD-2 Protein, Human | O15263 (G24-P64) | ≥ 95%, as determined by reducing SDS-PAGE. |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Erythrasma |
|
|
| Tinea Pedis |
|
|
| Acute Pericementitis |
|
|
| Leukorrhea |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS03681 | DEFB4B Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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