PPIH - peptidylprolyl isomerase H Gene

Homo sapiens

Also known as CYPH; CYP-20; USA-CYP; SnuCyp-20

Gene ID: 10465 | Gene type: protein coding

About PPIH

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:42,658,423-42,681,654 (from NCBI)

This gene has 20 transcripts (splice variants), 207 orthologues and 22 paralogues. Ubiquitous expression in bone marrow (RPKM 2.8), lymph node (RPKM 2.7) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008]

PPIH Products(2)

mRNA	Protein	Name
NM_001330510.2	NP_001317439.1	peptidyl-prolyl cis-trans isomerase H isoform 2
NM_006347.4	NP_006338.1	peptidyl-prolyl cis-trans isomerase H isoform 1

PPIH Protein Structure

Pro_isomerase

0
100
177 a.a.

Protein Preferred Names

Protein Names

peptidyl-prolyl cis-trans isomerase H

PPIase h

Recombinant PPIH Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71029	PPIH Protein, Human (His)	O43447 (M1-M177)	≥95%

Related Diseases

Diseases

Alias

Myxosarcoma

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10953	PPIH Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PPIH	VGNC	VGNC:33200
Canis familiaris	PPIH	VGNC	VGNC:44854
Mus musculus	PPIH	MGD	MGI:106499
Felis catus	PPIH	VGNC	VGNC:80316
Rattus norvegicus	PPIH	RGD	RGD:1564921
Macaca mulatta	PPIH	VGNC	VGNC:103846
Others	PPIH	NCBI