CLGN - calmegin Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1047

About CLGN

Cytogenetic location: 4q31.1 Genomic coordinates (GRCh38): 4:140,388,453-140,427,648 (from NCBI)

This gene has 3 transcripts (splice variants), 194 orthologues and 3 paralogues. Biased expression in testis (RPKM 66.0), heart (RPKM 22.6) and 2 other tissues.

Summary

Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. [provided by RefSeq, Jul 2008]

CLGN Products (2)

mRNA Protein Name
NM_001130675.2 NP_001124147.1 calmegin precursor
NM_004362.3 NP_004353.1 calmegin precursor

CLGN Protein Structure

Calreticulin

Calreticulin: Calreticulin family (60 - 429)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 610 a.a.
Protein Preferred Names Protein Names

calmegin

  • testis tissue sperm-binding protein Li 79P

Recombinant CLGN Proteins

Cat. No. Product Name Accession Purity
HY-P7709 Calmegin/CLGN Protein, Human (HEK293, His) O14967-1 (E20-W471) ≥ 90%, as determined by reducing SDS-PAGE.

CLGN Antibodies

Cat. No. Product Name Application Reactivity
HY-P82551 Calmegin Antibody (YA2296) WB, IHC-P, ICC/IF, IP Human, Mouse, Rat
HY-P83820 Calmegin Antibody (YA3517) WB, IHC-P, ICC/IF, ELISA Human
HY-P83820A Calmegin Antibody (YA3517)(PBS only) WB, IHC-P, ICC/IF, ELISA Human

Related Diseases

Diseases Alias
Colloid Adenoma

  • Macrofollicular Adenoma
Carotid Artery Dissection

  • Dissection Of Carotid Artery
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02802 CLGN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08516 MMP1 Human Pre-designed siRNA Set A / Unkown
HY-RS08517 Mmp1 Rat Pre-designed siRNA Set A / Unkown
HY-RS18919 Clgn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25409 Clgn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CLGN VGNC VGNC:60957
Mus musculus CLGN MGD MGI:107472
Macaca mulatta CLGN VGNC VGNC:71253
Rattus norvegicus CLGN RGD RGD:1592643
Canis familiaris CLGN VGNC VGNC:39336
Bos taurus CLGN VGNC VGNC:27437
Others CLGN NCBI