CLGN - calmegin Gene

Homo sapiens

Gene ID: 1047 | Gene type: protein coding

About CLGN

Cytogenetic location: 4q31.1 Genomic coordinates (GRCh38): 4:140,388,453-140,427,648 (from NCBI)

This gene has 3 transcripts (splice variants), 194 orthologues and 3 paralogues. Biased expression in testis (RPKM 66.0), heart (RPKM 22.6) and 2 other tissues.

Summary

Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. [provided by RefSeq, Jul 2008]

CLGN Products(2)

mRNA	Protein	Name
NM_001130675.2	NP_001124147.1	calmegin precursor
NM_004362.3	NP_004353.1	calmegin precursor

CLGN Protein Structure

Calreticulin

0
100
200
300
400
500
610 a.a.

Protein Preferred Names

Protein Names

calmegin

testis tissue sperm-binding protein Li 79P

Recombinant CLGN Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7709	Calmegin/CLGN Protein, Human (HEK293, His)	O14967-1 (E20-W471)	≥95%

Related Diseases

Diseases

Alias

Colloid Adenoma

Macrofollicular Adenoma

Carotid Artery Dissection

Dissection Of Carotid Artery

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02802	CLGN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CLGN	VGNC	VGNC:60957
Mus musculus	CLGN	MGD	MGI:107472
Macaca mulatta	CLGN	VGNC	VGNC:71253
Rattus norvegicus	CLGN	RGD	RGD:1592643
Canis familiaris	CLGN	VGNC	VGNC:39336
Bos taurus	CLGN	VGNC	VGNC:27437
Others	CLGN	NCBI