IFI44 - interferon induced protein 44 Gene

Also Known as p44; TLDC5; MTAP44

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10561

About IFI44

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:78,649,789-78,664,078 (from NCBI)

This gene has 9 transcripts (splice variants), 1023 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 19.2), spleen (RPKM 17.3) and 24 other tissues.

Summary

Predicted to be involved in immune response. Predicted to act upstream of or within response to bacterium. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

IFI44 Products (1)

mRNA Protein Name
NM_006417.5 NP_006408.3 interferon-induced protein 44

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IFI44 Protein Structure

TLD

TLD: TLD (26 - 151)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 444 a.a.
Protein Preferred Names Protein Names

interferon-induced protein 44

  • TBC/LysM-associated domain containing 5

IFI44 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
IFI44 Q8TCB0 MAGEA11 Homo sapiens P43364
Y2H Array
32296183
Intra
IFI44 Q8TCB0 MAGEA11 Homo sapiens P43364
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Multisystem Inflammatory Syndrome In Children

  • Mis-C

  • Multisystem Inflammatory Disorder In Children And Adolescents

  • Paediatric Inflammatory Multisystemic Syndrome

  • Mic
Hepatitis D

  • Delta Hepatitis

  • Hepatitis Delta

  • Hdv

  • Hepatitis D Virus

  • Hepatitis D Infection
Potocki-Shaffer Syndrome

  • Proximal 11p Deletion Syndrome

  • Chromosome 11p11.2 Deletion Syndrome

  • Pss

  • 11p11.2 Deletion

  • P11pds

  • Defect11 Syndrome

  • Deletion Of Chromosome 11p11.2

  • POSHS
Limited Scleroderma

  • Limited Cutaneous Systemic Sclerosis

  • Limited Systemic Sclerosis

  • Systemic Sclerosis Sine Scleroderma

  • Crest Syndrome

  • Limited Cutaneous Systemic Scleroderma

  • Scleroderma, Limited

  • Systemic Sclerosis, Limited

  • Progressive Systemic Sclerosis Sine Scleroderma

  • Scleroderma, Sine

  • Crest - [Calcinosis, Raynaud Phenomenon, Oesophageal Dysmotility, Sclerodactyly, And Telangiectasia] Syndrome

  • Crst - [Calcinosis, Raynaud Phenomenon, Sclerodactyly And Telangiectasia] Syndrome
Aicardi-Goutieres Syndrome

  • Aicardi Goutieres Syndrome

  • Cree Encephalitis

  • Aicardi-Goutières Syndrome

  • Encephalopathy With Basal Ganglia Calcification

  • Ags

  • Encephalopathy With Intracranial Calcification And Chronic Lymphocytosis Of Cerebrospinal Fluid

  • Pseudotoxoplasmosis Syndrome

  • Encephalopathy, Familial Infantile, With Calcification Of Basal Ganglia And Chronic Cerebrospinal Fluid Lymphocytosis

  • Familial Infantile Encephalopathy With Intracranial Calcification And Chronic Cerebrospinal Fluid Lymphocytosis

  • Aicardi-Goutieres Syndrome 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06556 IFI44 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06557 IFI44L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21868 Ifi44l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22569 Ifi44 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28385 Ifi44l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29088 Ifi44 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus IFI44 VGNC VGNC:30045
Rattus norvegicus IFI44 RGD RGD:1310523
Macaca mulatta IFI44 VGNC VGNC:73400
Felis catus IFI44 VGNC VGNC:62873
Mus musculus IFI44 MGD MGI:2443016
Canis familiaris IFI44 VGNC VGNC:41873
Others IFI44 NCBI