LILRA3 - leukocyte immunoglobulin like receptor A3 Gene
Also Known as HM31; HM43; ILT6; LIR4; CD85E; ILT-6; LIR-4
Species: Homo sapiens
About LILRA3
Summary
This gene encodes a member of a family of immunoreceptors that are expressed predominantly in monocytes and B cells, and at lower levels in dendritic cells and natural killer cells. The encoded protein lacks the transmembrane region found in Other members of this family. It acts as a soluble receptor for class I major histocompatibility complex (MHC) antigens. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and is polymorphic in human populations, with many individuals containing a deletion of this genomic region. [provided by RefSeq, Mar 2014]
LILRA3 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001172654.2 | NP_001166125.1 | leukocyte immunoglobulin-like receptor subfamily A member 3 isoform 2 precursor |
| NM_006865.4 | NP_006856.3 | leukocyte immunoglobulin-like receptor subfamily A member 3 isoform 1 precursor |
LILRA3 Protein Structure
Ig_2: Immunoglobulin domain (45 - 135)
Ig_3: Immunoglobulin domain (141 - 216)
Ig_2: Immunoglobulin domain (242 - 334)
Ig_3: Immunoglobulin domain (343 - 417)
- 0
- 100
- 200
- 300
- 400
- 456 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
leukocyte immunoglobulin-like receptor subfamily A member 3 |
|
Recombinant LILRA3 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P70162 | LILRA3/CD85e/ILT6 Protein, Human (HEK293, His) | Q8N6C8-1/AAH28208.1 (T19-E439) | ≥ 90%, as determined by reducing SDS-PAGE. |
| HY-P72393 | LILRA3/CD85e/ILT6 Protein, Human (Biotinylated, HEK293, His-Avi) | Q8N6C8-1/AAH28208.1 (G24-E439) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P77984 | LILRA3/CD85e/ILT6 Protein, Human (HEK293, His-Avi) | Q8N6C8-1 (G24-E439) | ≥ 95%, as determined by Bis-Tris PAGE. |