Wnt2 - Wnt family member 2 Gene

Also Known as Wnt

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114487

Summary

Predicted to enable cytokine activity and Frizzled binding activity. Involved in lung development and positive regulation of endothelial cell proliferation. Located in cytoplasm. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and urinary system Cancer. Orthologous to human WNT2 (Wnt family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Wnt2 Products (1)

mRNA Protein Name
XM_575397.8 XP_575397.1 protein Wnt-2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in lung development IEP
IEP: Inferred from expression pattern
1377452 RGD
involved in positive regulation of endothelial cell proliferation IMP
IMP: Inferred from mutant phenotype
18302287 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Wnt-2

  • wingless-related MMTV integration site 2

  • wingless-type MMTV integration site 2

  • wingless-type MMTV integration site family member 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-183400 BIM-46174 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wnt2 NCBI NCBI:7472