MRGPRX4 - MAS related GPR family member X4 Gene

Also Known as GPCR; MRGX4; SNSR6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 117196

About MRGPRX4

Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:18,172,837-18,174,280 (from NCBI)

This gene has 1 transcript (splice variant), 444 orthologues and 10 paralogues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within chemosensory behavior and hematopoietic progenitor cell differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

MRGPRX4 Products (1)

mRNA Protein Name
NM_054032.3 NP_473373.2 mas-related G-protein coupled receptor member X4

MRGPRX4 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (44 - 272)

  • 0
  • 100
  • 200
  • 300
  • 322 a.a.
Protein Preferred Names Protein Names

mas-related G-protein coupled receptor member X4

  • G protein-coupled receptor MRGX4

Related Diseases

Diseases Alias
Congenital Disorder Of Glycosylation, Type Ip

  • CDG1P

  • Congenital Disorder Of Glycosylation Ip

  • Congenital Disorder Of Glycosylation 1p

  • Alg11-Cdg

  • Cdg-Ip

  • Congenital Disorder Of Glycosylation Type Ip

  • Cdg Syndrome Type Ip

  • Carbohydrate Deficient Glycoprotein Syndrome Type Ip

  • Congenital Disorder Of Glycosylation Type 1p

  • Cdgip

  • Cdg Ip

  • Glycosylation, Congenital Disorder Of, Type Ip
Intrahepatic Cholestasis Of Pregnancy

  • Recurrent Intrahepatic Cholestasis Of Pregnancy

  • Gravidic Intrahepatic Cholestasis

  • Pregnancy-Related Cholestasis

  • Icp

  • Pregnancy Related Cholestasis

  • Cholestasis, Intrahepatic Of Pregnancy

  • Familial Intrahepatic Cholestasis Of Pregnancy

  • Familial Recurrent Intrahepatic Cholestasis Of Pregnancy

  • Ricp

  • Obstetric Cholestasis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-156907 ZINC49534341 Antagonist 99.40% Unkown
HY-148244 MS47134 99.69% Unkown
HY-147051 Nelremagpran 99.94% Unkown
HY-145997 MRGPRX4 modulator-1 98.96% Unkown
HY-155480 PSB-22034 Agonist 99.61% Unkown
HY-173003 EP-3945 Agonist 99.17% Unkown
HY-183050 HEP-50768 Antagonist 99.17% Unkown
HY-W354369 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid Antagonist 99.90% Unkown
HY-175672 MRGPRX4 modulator-3 Modulator / Unkown
HY-RS08652 MRGPRX4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MRGPRX4 RGD RGD:632284
Others MRGPRX4 NCBI