LCN8 - lipocalin 8 Gene

Also Known as EP17; LCN5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 138307

About LCN8

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:136,754,386-136,758,543 (from NCBI)

This gene has 5 transcripts (splice variants), 172 orthologues and 12 paralogues. Low expression observed in reference dataset.

Summary

Members of the Lipocalin Family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]

LCN8 Products (2)

mRNA Protein Name
NM_001345934.2 NP_001332863.1 epididymal-specific lipocalin-8 isoform 1 precursor
NM_178469.4 NP_848564.2 epididymal-specific lipocalin-8 isoform 2

LCN8 Protein Structure

Lipocalin

Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (11 - 131)

  • 0
  • 100
  • 152 a.a.
Protein Preferred Names Protein Names

epididymal-specific lipocalin-8

  • epididymis secretory sperm binding protein

Recombinant LCN8 Proteins

Cat. No. Product Name Accession Purity
HY-P77056 LCN8 Protein, Human (HEK293, His) Q6JVE9-2/NP_848564.2 (M1-I152) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Night Blindness, Congenital Stationary, Autosomal Dominant 1

  • Congenital Stationary Night Blindness Autosomal Dominant 1

  • CSNBAD1

  • Rhodopsin-Related Congenital Stationary Night Blindness

  • Night Blindness, Congenital Stationary, Rhodopsin-Related

  • Blindness, Night, Stationary, Congenital, Autosomal Dominant, Type 1
Alopecia, Neurologic Defects, And Endocrinopathy Syndrome

  • Ane Syndrome

  • ANES

  • Alopecia-Progressive Neurological Defect-Endocrinopathy Syndrome

  • Alopecia-Progressive Neurological Defect-Endocrinopathy

  • Endocrine System Diseases
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07559 LCN8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20293 Lcn8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26801 Lcn8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta LCN8 VGNC VGNC:74136
Rattus norvegicus LCN8 RGD RGD:1306747
Mus musculus LCN8 MGD MGI:2135945
Bos taurus LCN8 VGNC VGNC:59344
Canis familiaris LCN8 VGNC VGNC:42613
Others LCN8 NCBI