LCN8 - lipocalin 8 Gene

Homo sapiens

Also known as EP17; LCN5

Gene ID: 138307 | Gene type: protein coding

About LCN8

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:136,754,386-136,758,543 (from NCBI)

This gene has 5 transcripts (splice variants), 172 orthologues and 12 paralogues. Low expression observed in reference dataset.

Summary

Members of the lipocalin family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]

LCN8 Products(2)

mRNA	Protein	Name
NM_001345934.2	NP_001332863.1	epididymal-specific lipocalin-8 isoform 1 precursor
NM_178469.4	NP_848564.2	epididymal-specific lipocalin-8 isoform 2

LCN8 Protein Structure

Lipocalin

0
100
152 a.a.

Protein Preferred Names

Protein Names

epididymal-specific lipocalin-8

epididymis secretory sperm binding protein

Recombinant LCN8 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77056	LCN8 Protein, Human (HEK293, His)	Q6JVE9 (A26-I175)	≥95%

Related Diseases

Diseases

Alias

Night Blindness, Congenital Stationary, Autosomal Dominant 1

Congenital Stationary Night Blindness Autosomal Dominant 1	CSNBAD1
Rhodopsin-Related Congenital Stationary Night Blindness	Night Blindness, Congenital Stationary, Rhodopsin-Related
Blindness, Night, Stationary, Congenital, Autosomal Dominant, Type 1

Alopecia, Neurologic Defects, And Endocrinopathy Syndrome

Ane Syndrome	ANES
Alopecia-Progressive Neurological Defect-Endocrinopathy Syndrome	Alopecia-Progressive Neurological Defect-Endocrinopathy
Endocrine System Diseases

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07559	LCN8 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	LCN8	VGNC	VGNC:74136
Rattus norvegicus	LCN8	RGD	RGD:1306747
Mus musculus	LCN8	MGD	MGI:2135945
Bos taurus	LCN8	VGNC	VGNC:59344
Canis familiaris	LCN8	VGNC	VGNC:42613
Others	LCN8	NCBI