Mfng - MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17305

Summary

Predicted to enable O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity. Involved in marginal zone B cell differentiation and regulation of Notch signaling pathway. Acts upstream of or within blastocyst formation; positive regulation of Notch signaling pathway; and positive regulation of protein binding activity. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of Golgi membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and sensory organ. Orthologous to human MFNG (MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mfng Products (2)

mRNA Protein Name
NM_001411378.1 NP_001398307.1 beta-1,3-N-acetylglucosaminyltransferase manic fringe isoform 2
NM_008595.3 NP_032621.1 beta-1,3-N-acetylglucosaminyltransferase manic fringe isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity IDA
IDA: Inferred from direct assay
16221665 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21946561 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within blastocyst formation IMP
IMP: Inferred from mutant phenotype
27869233 MGI
involved in marginal zone B cell differentiation IMP
IMP: Inferred from mutant phenotype
19217325 MGI
acts upstream of or within positive regulation of Notch signaling pathway IDA
IDA: Inferred from direct assay
15574878 MGI
acts upstream of or within positive regulation of protein binding IDA
IDA: Inferred from direct assay
15574878 MGI
involved in regulation of Notch signaling pathway IMP
IMP: Inferred from mutant phenotype
28089369 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-1,3-N-acetylglucosaminyltransferase manic fringe

  • O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

  • manic fringe homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08385 MFNG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21375 Mfng Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27894 Mfng Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mfng NCBI NCBI:4242