Msl3 - MSL complex subunit 3 Gene

Also Known as Msl31; Msl3l1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17692

Summary

Predicted to enable DNA binding activity; Histone Acetyltransferase activity (H4-K16 specific); and methylated histone binding activity. Predicted to be involved in heterochromatin assembly and histone modification. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleus. Predicted to be part of MSL complex and NuA4 Histone Acetyltransferase complex. Is expressed in embryo; limb; and limb mesenchyme. Human ortholog(s) of this gene implicated in Basilicata-Akhtar syndrome. Orthologous to human MSL3 (MSL complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]

Msl3 Products (13)

mRNA Protein Name
NM_001370791.1 NP_001357720.1 male-specific lethal 3 homolog isoform 1
NM_001370792.1 NP_001357721.1 male-specific lethal 3 homolog isoform 2
NM_001370793.1 NP_001357722.1 male-specific lethal 3 homolog isoform 3
NM_001370794.1 NP_001357723.1 male-specific lethal 3 homolog isoform 4
NM_001370795.1 NP_001357724.1 male-specific lethal 3 homolog isoform 6
NM_001370796.1 NP_001357725.1 male-specific lethal 3 homolog isoform 7
NM_001370797.1 NP_001357726.1 male-specific lethal 3 homolog isoform 8
NM_001370798.1 NP_001357727.1 male-specific lethal 3 homolog isoform 9
NM_001370799.1 NP_001357728.1 male-specific lethal 3 homolog isoform 10
NM_001411770.1 NP_001398699.1 male-specific lethal 3 homolog isoform 11
NM_001411771.1 NP_001398700.1 male-specific lethal 3 homolog isoform 12
NM_001411772.1 NP_001398701.1 male-specific lethal 3 homolog isoform 13
NM_010832.6 NP_034962.2 male-specific lethal 3 homolog isoform 5

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
24842875 MGI
Cellular Component GO Annotation Evidence References Source
part of MSL complex IDA
IDA: Inferred from direct assay
24842875 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

male-specific lethal 3 homolog

  • male-specific lethal-3 homolog 1

  • male-specific lethal-3 protein-like 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08718 MSL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20775 Msl3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27289 Msl3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msl3 NCBI NCBI:10943