Prok2 - prokineticin 2 Gene

Also Known as Bv8; PK2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192206

Summary

Enables G protein-coupled receptor binding activity. Predicted to be involved in several processes, including angiogenesis; endothelial cell proliferation; and positive regulation of smooth muscle contraction. Predicted to act upstream of or within circadian rhythm. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 4 with or without anosmia. Orthologous to human PROK2 (prokineticin 2). [provided by Alliance of Genome Resources, Apr 2022]

Prok2 Products (2)

mRNA Protein Name
NM_001037541.2 NP_001032630.1 prokineticin-2 isoform 1 precursor
NM_138852.2 NP_620207.1 prokineticin-2 isoform 2 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor binding IDA
IDA: Inferred from direct assay
12054613 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prokineticin-2

  • homolog of mouse Bv8 (Bombina variegata 8 kDa)

  • homolog of mouse Bv8 (Bombina variegata 8 kDa)

  • prokineticin 2

  • prokineticin 2 beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11195 PROK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21699 Prok2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28217 Prok2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prok2 NCBI NCBI:60675