Rax - retina and anterior neural fold homeobox Gene

Also Known as Rx; ey1; ey-1; 7530406A22Rik; E130303K03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19434

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including camera-type eye development; hypothalamus development; and limb development. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; eye; genitourinary system; hemolymphoid system; and neural ectoderm. Human ortholog(s) of this gene implicated in isolated microphthalmia 3. Orthologous to human RAX (retina and anterior neural fold homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Rax Products (1)

mRNA Protein Name
NM_013833.2 NP_038861.2 retinal homeobox protein Rx

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
15789424 MGI
acts upstream of or within camera-type eye development IMP
IMP: Inferred from mutant phenotype
640224 MGI
acts upstream of or within hypothalamus development IMP
IMP: Inferred from mutant phenotype
925203 MGI
acts upstream of or within limb development IMP
IMP: Inferred from mutant phenotype
13970082 MGI
acts upstream of or within pattern specification process IMP
IMP: Inferred from mutant phenotype
13970082 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinal homeobox protein Rx

  • Rx/rax homeoprotein

  • eyeless 1

  • retina and anterior neural fold homeobox protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W130236 Methylene Violet 3RAX Inhibitor 95.54% Unkown
HY-RS11157 PRKRA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11711 RAX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11712 RAX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17731 Rax Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24196 Rax Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rax NCBI NCBI:30062