1. Gene
  2. FSTL4 - follistatin like 4 Gene

FSTL4 - follistatin like 4 Gene

Homo sapiens
Gene ID: 23105 | Gene type: protein coding

About FSTL4

This gene has 7 transcripts (splice variants), 204 orthologues and 6 paralogues. Biased expression in brain (RPKM 2.5), urinary bladder (RPKM 1.7) and 8 other tissues.

Summary

Predicted to enable brain-derived neurotrophic factor binding activity and calcium ion binding activity. Predicted to be involved in cell differentiation. Predicted to act upstream of or within negative regulation of brain-derived neurotrophic factor receptor signaling pathway; negative regulation of collateral sprouting; and negative regulation of dendritic spine development. Predicted to be located in extracellular region and secretory granule. [provided by Alliance of Genome Resources, Apr 2022]

FSTL4 Products(1)

mRNA Protein Name
NM_015082.2 NP_055897.1 follistatin-related protein 4 precursor

FSTL4 Protein Structure

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (93 - 133)

Ig_2

Ig_2: Immunoglobulin domain (255 - 339)

I-set

I-set: Immunoglobulin I-set domain (341 - 429)

  • 0
  • 200
  • 400
  • 600
  • 842 a.a.
Protein Preferred Names Protein Names

follistatin-related protein 4

follistatin-like protein 4

Related Diseases

Diseases Alias
Ileum Cancer

Ileal Neoplasm

Malignant Neoplasm Of Ileum

Ileal Cancer

Ileal Neoplasms

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris FSTL4 VGNC VGNC:41000
Macaca mulatta FSTL4 VGNC VGNC:72759
Rattus norvegicus FSTL4 RGD RGD:1307227
Felis catus FSTL4 VGNC VGNC:62382
Mus musculus FSTL4 MGD MGI:2443199
Bos taurus FSTL4 VGNC VGNC:54435