FSTL4 - follistatin like 4 Gene
Species: Homo sapiens
About FSTL4
This gene has 7 transcripts (splice variants), 204 orthologues and 6 paralogues. Biased expression in brain (RPKM 2.5), urinary bladder (RPKM 1.7) and 8 other tissues.
Summary
Predicted to enable brain-derived neurotrophic factor binding activity and calcium ion binding activity. Predicted to be involved in cell differentiation. Predicted to act upstream of or within negative regulation of brain-derived neurotrophic factor receptor signaling pathway; negative regulation of collateral sprouting; and negative regulation of dendritic spine development. Predicted to be located in extracellular region and secretory granule. [provided by Alliance of Genome Resources, Apr 2022]
FSTL4 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_015082.2 | NP_055897.1 | follistatin-related protein 4 precursor |
FSTL4 Protein Structure
Kazal_2: Kazal-type serine protease inhibitor domain (93 - 133)
Ig_2: Immunoglobulin domain (255 - 339)
I-set: Immunoglobulin I-set domain (341 - 429)
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- 200
- 400
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- 842 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
follistatin-related protein 4 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Ileum Cancer |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | FSTL4 | VGNC | VGNC:41000 |
| Macaca mulatta | FSTL4 | VGNC | VGNC:72759 |
| Rattus norvegicus | FSTL4 | RGD | RGD:1307227 |
| Felis catus | FSTL4 | VGNC | VGNC:62382 |
| Mus musculus | FSTL4 | MGD | MGI:2443199 |
| Bos taurus | FSTL4 | VGNC | VGNC:54435 |
| Others | FSTL4 | NCBI |