Ldlrad3 - low density lipoprotein receptor class A domain containing 3 Gene

Also Known as Lrad3; 6430500P08

Species: Mus musculus

Gene Type: protein coding
Gene ID: 241576

Summary

Enables amyloid-beta binding activity. Acts upstream of or within receptor-mediated endocytosis and regulation of protein processing. Located in plasma membrane. Is expressed in cranial ganglion; dorsal root ganglion; and gut. Orthologous to human LDLRAD3 (low density lipoprotein receptor class A domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Ldlrad3 Products (2)

mRNA Protein Name
NM_001290784.1 NP_001277713.1 low-density lipoprotein receptor class A domain-containing protein 3 isoform b precursor
NM_178886.3 NP_849217.2 low-density lipoprotein receptor class A domain-containing protein 3 isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables amyloid-beta binding IDA
IDA: Inferred from direct assay
21795536 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
26854353 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within receptor-mediated endocytosis IDA
IDA: Inferred from direct assay
21795536 MGI
acts upstream of or within regulation of protein processing IDA
IDA: Inferred from direct assay
21795536 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
21795536 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
21795536 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

low-density lipoprotein receptor class A domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07578 LDLRAD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21244 Ldlrad3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27761 Ldlrad3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991766 Anti-Venezuelan equine encephalitis virus E2 protein Antibody (VEEV-57) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ldlrad3 NCBI NCBI:143458