Bank1 - B cell scaffold protein with ankyrin repeats 1 Gene

Also Known as BANK; AVIEF; A530094C12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 242248

Summary

Predicted to enable enzyme binding activity; signaling adaptor activity; and signaling receptor binding activity. Acts upstream of or within several processes, including negative regulation of B cell activation; negative regulation of gene expression; and regulation of intracellular signal transduction. Predicted to be located in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in autoimmune disease (multiple) and systemic scleroderma (multiple). Orthologous to human BANK1 (B cell scaffold protein with ankyrin repeats 1). [provided by Alliance of Genome Resources, Apr 2022]

Bank1 Products (2)

mRNA Protein Name
NM_001033350.3 NP_001028522.2 B-cell scaffold protein with ankyrin repeats isoform 1
NM_001310749.1 NP_001297678.1 B-cell scaffold protein with ankyrin repeats isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of MAPK cascade IMP
IMP: Inferred from mutant phenotype
24227780 MGI
acts upstream of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
24227780 MGI
acts upstream of or within negative regulation of B cell activation IGI
IGI: Inferred from genetic interaction
16546095 MGI
acts upstream of or within negative regulation of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
24227780 MGI
acts upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IGI
IGI: Inferred from genetic interaction
16546095 MGI
acts upstream of or within negative regulation of translational initiation IMP
IMP: Inferred from mutant phenotype
24227780 MGI
acts upstream of phosphatidylinositol 3-kinase/protein kinase B signal transduction IGI
IGI: Inferred from genetic interaction
16546095 MGI
acts upstream of or within positive regulation of MAPK cascade IMP
IMP: Inferred from mutant phenotype
24227780 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

B-cell scaffold protein with ankyrin repeats

  • B-cell scaffold protein with ankyrin repeats 1 delta 2 transcript

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01362 BANK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21495 Bank1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28013 Bank1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W725041 Methiozolin / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bank1 NCBI NCBI:55024