Serpina1 - serpin family A member 1 Gene
Also Known as Pi; AAT; Spi1
Species: Rattus norvegicus
Summary
Enables serine-type endopeptidase inhibitor activity. Involved in several processes, including negative regulation of serine-type endopeptidase activity; response to estradiol; and response to methanol. Located in extracellular space. Used to study pulmonary hypertension. Biomarker of asthma; osteoarthritis; pancreatitis (multiple); primary hyperaldosteronism; and proteinuria. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; chronic obstructive pulmonary disease (multiple); human immunodeficiency virus infectious disease; inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (Serpin family A member 1). [provided by Alliance of Genome Resources, Apr 2022]
Serpina1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_022519.2 | NP_071964.2 | alpha-1-antiproteinase precursor |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
alpha-1-antiproteinase |
|
|
Recombinant Serpina1 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P74556 | Serpin A1 Protein, Rat (HEK293, His) | P17475 (E25-R411) | ≥ 95%, as determined by reducing SDS-PAGE. |
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-132604A | Fazirsiran sodium | 93.25% | Unkown | |
| HY-107098 | PPL-100 free acid | / | Unkown | |
| HY-RS12696 | SERPINA1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-174540 | Human SERPINA1 mRNA | / | Unkown | |
| HY-RS23630 | Serpina1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29511 | Serpina1a Mouse Pre-designed siRNA Set A | / | Unkown |
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