Serpina3n - serine (or cysteine) peptidase inhibitor, clade A, member 3N Gene

Also Known as SPI3; Spin3; CPi-26; Spin2c; Spi-2.2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24795

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to organic cyclic compound; and response to vitamin B6. Located in extracellular space. Used to study adult respiratory distress syndrome. Biomarker of uveitis. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; cystic fibrosis; and vasculitis. Orthologous to human SERPINA3 (Serpin family A member 3). [provided by Alliance of Genome Resources, Apr 2022]

Serpina3n Products (2)

mRNA Protein Name
NM_031531.3 NP_113719.3 serine protease inhibitor A3N precursor
NM_031531.3 NP_113719.3 serine protease inhibitor A3N precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to cAMP IEP
IEP: Inferred from expression pattern
11578771 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: Inferred from expression pattern
11578771 RGD
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
10547273 RGD
involved in cellular response to interleukin-6 IEP
IEP: Inferred from expression pattern
8611141 RGD
involved in cellular response to type II interferon IEP
IEP: Inferred from expression pattern
7619083 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
12127095 RGD
involved in response to vitamin B6 IEP
IEP: Inferred from expression pattern
21462331 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
2439511 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine protease inhibitor A3N

  • SPI-3

  • contrapsin-like protease inhibitor 6

  • serine protease inhibitor 2c

  • serine protease inhibitor 3

  • serpin A3N

  • serpina3n-like protein

Recombinant Serpina3n Proteins

Cat. No. Product Name Accession Purity
HY-P74558 Serpin A3N Protein, Rat (HEK293, His) P09006 (T30-K418) ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150514 ARN1468 Inhibitor 98.96% Unkown