SIGLEC9 - sialic acid binding Ig like lectin 9 Gene

Homo sapiens

Also known as CD329; CDw329; FOAP-9; siglec-9; OBBP-LIKE

Gene ID: 27180 | Gene type: protein coding

About SIGLEC9

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,119,778-51,136,263 (from NCBI)

This gene has 3 transcripts (splice variants), 84 orthologues and 16 paralogues. Broad expression in appendix (RPKM 3.6), spleen (RPKM 2.9) and 15 other tissues.

Summary

Predicted to enable monosaccharide binding activity and sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis, engulfment. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SIGLEC9 Products(2)

mRNA	Protein	Name
NM_001198558.1	NP_001185487.1	sialic acid-binding Ig-like lectin 9 isoform 1 precursor
NM_014441.3	NP_055256.1	sialic acid-binding Ig-like lectin 9 isoform 2 precursor

SIGLEC9 Protein Structure

V-set

Ig_3

Ig_2

0
100
200
300
400
463 a.a.

Protein Preferred Names

Protein Names

sialic acid-binding Ig-like lectin 9

protein FOAP-9

Recombinant SIGLEC9 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70739	Siglec-9 Protein, Human (HEK293, His)	AAH35365.2 (Q18-G348)	≥95%
HY-P78039	Siglec-9 Protein, Human (HEK293, Fc)	Q9Y336 (Q18-G348)	≥95%
HY-P78040	Siglec-9 Protein, Human (HEK293, His-Avi)	Q9Y336 (Q18-G348)	≥95%
HY-P701040	Siglec-9 Protein, Human (Biotinylated, HEK293, His-Avi)	Q9Y336-1 (Q18-G348)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12907	SIGLEC9 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SIGLEC9	MGD	MGI:1932475

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