Selenoi - selenoprotein I Gene

Also Known as Ept1; SELI; D5Wsu178e; mKIAA1724; 4933402G07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 28042

Summary

The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016]

Selenoi Products (1)

mRNA Protein Name
NM_027652.3 NP_081928.2 ethanolaminephosphotransferase 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ethanolaminephosphotransferase activity IMP
IMP: Inferred from mutant phenotype
38582453 MGI
Biological Process GO Annotation Evidence References Source
involved in ether lipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
38582453 MGI
involved in myelination IMP
IMP: Inferred from mutant phenotype
38582453 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ethanolaminephosphotransferase 1

  • ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12636 SELENOI Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21253 Selenoi Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27770 Selenoi Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Selenoi NCBI NCBI:85465