METRNL - meteorin like, glial cell differentiation regulator Gene

Homo sapiens

Gene ID: 284207 | Gene type: protein coding

About METRNL

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:83,079,609-83,095,122 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 254 orthologues and 1 paralogue. Ubiquitous expression in colon (RPKM 12.0), kidney (RPKM 11.4) and 25 other tissues.

Summary

Predicted to enable hormone activity. Predicted to be involved in several processes, including brown fat cell differentiation; energy homeostasis; and positive regulation of brown fat cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

METRNL Products(2)

mRNA	Protein	Name
NM_001004431.3	NP_001004431.1	meteorin-like protein isoform 1 precursor
NM_001363853.2	NP_001350782.1	meteorin-like protein isoform 2

Protein Preferred Names

Protein Names

meteorin-like protein

cometin

Recombinant METRNL Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71569	METRNL/Meteorin-like Protein, Human (His-SUMO)	Q641Q3 (46Q-311D)	≥95%

Related Diseases

Diseases

Alias

Bardet-Biedl Syndrome 12

BBS12	Bardet-Biedl Syndrome
Bbs	Bardet-Biedl Syndrome, Type 12

Bladder Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Bladder	Epidermoid Carcinoma Of The Urinary Bladder
Carcinoma Squamous Cell Bladder

Primary Cutaneous Amyloidosis

Plca	Primary Localized Cutaneous Amyloidosis
Familial Primary Localized Cutaneous Amyloidosis	Amyloidosis Ix
Lichen Amyloidosis Familial	Amyloidosis, Primary Cutaneous
Pca	Amyloidosis 9
Amyloidosis Familial Cutaneous Lichen	Fplca
Familial Lichen Amyloidosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08352	METRNL Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	METRNL	RGD	RGD:1359271
Felis catus	METRNL	VGNC	VGNC:63457
Macaca mulatta	METRNL	VGNC	VGNC:82184
Mus musculus	METRNL	MGD	MGI:2384806
Bos taurus	METRNL	VGNC	VGNC:31399
Others	METRNL	NCBI

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