GPR31 - G protein-coupled receptor 31 Gene

Also Known as HETER; HETER1; 12-HETER

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2853

About GPR31

Cytogenetic location: 6q27 Genomic coordinates (GRCh38): 6:167,155,247-167,157,980 (from NCBI)

This gene has 1 transcript (splice variant), 201 orthologues and 15 paralogues.

Summary

Enables G protein-coupled receptor activity and arachidonic acid binding activity. Involved in G protein-coupled receptor signaling pathway and response to acidic pH. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPR31 Products (1)

mRNA Protein Name
NM_005299.3 NP_005290.2 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
21712392 GOA
enables arachidonate binding IDA
IDA: Inferred from direct assay
21712392 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
28619714 GOA
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
21712392 GOA
involved in response to acidic pH IDA
IDA: Inferred from direct assay
31119277 GOA
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
21712392 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR31 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (31 - 282)

  • 0
  • 100
  • 200
  • 300
  • 319 a.a.
Protein Preferred Names Protein Names

12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor

  • 12-(S)-HETE acid receptor

Related Diseases

Diseases Alias
Ischemia

  • Acute Coronary Syndrome
Vulvar Dystrophy

  • Dystrophy Of Vulva
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS20941 Gpr31 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05701 GPR31 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27458 Gpr31 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GPR31 VGNC VGNC:41430
Macaca mulatta GPR31 VGNC VGNC:104403
Mus musculus GPR31 MGD MGI:1354372
Rattus norvegicus GPR31 RGD RGD:1305187
Bos taurus GPR31 VGNC VGNC:29582
Others GPR31 NCBI