LCN12 - lipocalin 12 Gene
生物種: Homo sapiens
About LCN12
This gene has 15 transcripts (splice variants), 156 orthologues and 12 paralogues. Biased expression in thyroid (RPKM 11.7), spleen (RPKM 1.8) and 4 other tissues.
Summary
Members of the Lipocalin Family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]
LCN12 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_178536.4 | NP_848631.2 | epididymal-specific lipocalin-12 precursor |
LCN12 Protein Structure
Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (40 - 183)
- 0
- 100
- 192 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
epididymal-specific lipocalin-12 |
|
関連疾患
| Diseases | Alias | |
|---|---|---|
| Extratemporal Epilepsy |
|
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| Corneal Ectasia |
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| Keratoconus |
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Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Macaca mulatta | LCN12 | VGNC | VGNC:74143 |
| Bos taurus | LCN12 | VGNC | VGNC:59222 |
| Mus musculus | LCN12 | MGD | MGI:1924951 |
| Rattus norvegicus | LCN12 | RGD | RGD:1589474 |
| Canis familiaris | LCN12 | VGNC | VGNC:55626 |
| Others | LCN12 | NCBI |