Pebp1 - phosphatidylethanolamine binding protein 1 Gene

Also Known as Pbp; HCNP; Rkip

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29542

Summary

Enables ATP binding activity; mitogen-activated protein kinase binding activity; and receptor serine/threonine kinase binding activity. Involved in several processes, including positive regulation of acetylcholine metabolic process; positive regulation of mitotic nuclear division; and regulation of intracellular signal transduction. Located in several cellular components, including mitochondrial outer membrane; rough endoplasmic reticulum; and synaptic vesicle. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in prostate Cancer. Orthologous to human PEBP1 (phosphatidylethanolamine binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pebp1 Products (1)

mRNA Protein Name
NM_017236.2 NP_058932.1 phosphatidylethanolamine-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
10622376 RGD
enables kinase binding IPI
IPI: Inferred from physical interaction
14654844 RGD
enables mitogen-activated protein kinase binding IDA
IDA: Inferred from direct assay
10490027 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
11585904 RGD
enables receptor serine/threonine kinase binding IPI
IPI: Inferred from physical interaction
27568556 RGD
enables signaling receptor binding IDA
IDA: Inferred from direct assay
10622376 RGD
Biological Process GO Annotation Evidence References Source
involved in MAPK cascade IDA
IDA: Inferred from direct assay
10490027 RGD
involved in eating behavior IEP
IEP: Inferred from expression pattern
16132681 RGD
involved in hippocampus development IEP
IEP: Inferred from expression pattern
18493952 RGD
involved in negative regulation of MAPK cascade IMP
IMP: Inferred from mutant phenotype
15886202 RGD
involved in negative regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
15886202 RGD
involved in positive regulation of acetylcholine biosynthetic process IDA
IDA: Inferred from direct assay
10622376 RGD
involved in positive regulation of acetylcholine metabolic process IDA
IDA: Inferred from direct assay
8888012 RGD
involved in positive regulation of cAMP/PKA signal transduction IMP
IMP: Inferred from mutant phenotype
14654844 RGD
involved in positive regulation of mitotic nuclear division IMP
IMP: Inferred from mutant phenotype
16916643 RGD
involved in regulation of the force of heart contraction IDA
IDA: Inferred from direct assay
16608915 RGD
involved in response to activity IEP
IEP: Inferred from expression pattern
17963288 RGD
involved in response to cAMP IEP
IEP: Inferred from expression pattern
7706975 RGD
involved in response to calcium ion IEP
IEP: Inferred from expression pattern
10622376 RGD
involved in response to corticosterone IEP
IEP: Inferred from expression pattern
18311602 RGD
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
11166120 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
18067547 RGD
involved in response to oxidative stress IEP
IEP: Inferred from expression pattern
18067547 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
11166120 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
11166120 RGD
involved in spermatid development IEP
IEP: Inferred from expression pattern
9508097 RGD
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
10639732 RGD
located in axon terminus IDA
IDA: Inferred from direct assay
11428049 RGD
located in cell surface IDA
IDA: Inferred from direct assay
11034991 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
7706975 RGD
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
11428049 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10622376 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
11428049 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylethanolamine-binding protein 1

  • 23 kDa morphine-binding protein

  • HCNPpp

  • P23K

  • PEBP-1

  • Raf-1 kinase inhibitor protein

  • hippocampal cholinergic neurostimulating peptide

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10313 PEBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18075 Pebp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24550 Pebp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pebp1 NCBI NCBI:5037