PDZRN4 - PDZ domain containing ring finger 4 Gene

Also Known as LNX4; SAMCAP3L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 29951

About PDZRN4

Cytogenetic location: 12q12 Genomic coordinates (GRCh38): 12:41,188,320-41,574,745 (from NCBI)

This gene has 5 transcripts (splice variants), 266 orthologues and 2 paralogues. Broad expression in prostate (RPKM 5.3), urinary bladder (RPKM 3.3) and 15 other tissues.

Summary

Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]

PDZRN4 Products (2)

mRNA Protein Name
NM_001164595.2 NP_001158067.1 PDZ domain-containing RING finger protein 4 isoform 1
NM_013377.4 NP_037509.3 PDZ domain-containing RING finger protein 4 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PDZRN4 Protein Structure

zf-RING_2

zf-RING_2: Ring finger domain (17 - 54)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (225 - 310)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (408 - 477)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1036 a.a.
Protein Preferred Names Protein Names

PDZ domain-containing RING finger protein 4

  • IMAGE5767589

Related Diseases

Diseases Alias
Vulvitis

  • Vulvitis Nos

  • Inflammation Of Vulva

  • Edeitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10308 PDZRN4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21168 Pdzrn4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27685 Pdzrn4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris PDZRN4 VGNC VGNC:44405
Macaca mulatta PDZRN4 VGNC VGNC:75898
Bos taurus PDZRN4 VGNC VGNC:55073
Mus musculus PDZRN4 MGD MGI:3056996
Rattus norvegicus PDZRN4 RGD RGD:1308860
Others PDZRN4 NCBI