NXPH1 - neurexophilin 1 Gene
Also Known as NPH1; Nbla00697
Species: Homo sapiens
About NXPH1
This gene has 5 transcripts (splice variants), 272 orthologues and 3 paralogues. Biased expression in adrenal (RPKM 15.5) and brain (RPKM 12.8).
Summary
This gene is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. [provided by RefSeq, Jul 2008]
NXPH1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_152745.3 | NP_689958.1 | neurexophilin-1 precursor |
NXPH1 Protein Structure
Neurexophilin: Neurexophilin (66 - 271)
- 0
- 100
- 200
- 271 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
neurexophilin-1 |
|
Recombinant NXPH1 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P71178 | NXPH1 Protein, Human (HEK293, His) | P58417 (A22-G271) | ≥ 95%, as determined by reducing SDS-PAGE. |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Constipation |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | NXPH1 | MGD | MGI:107492 |
| Bos taurus | NXPH1 | VGNC | VGNC:50069 |
| Felis catus | NXPH1 | VGNC | VGNC:63939 |
| Rattus norvegicus | NXPH1 | RGD | RGD:3218 |
| Canis familiaris | NXPH1 | VGNC | VGNC:44077 |
| Macaca mulatta | NXPH1 | VGNC | VGNC:81732 |
| Others | NXPH1 | NCBI |