2. Gene
  3. NXPH1 - neurexophilin 1 Gene

NXPH1 - neurexophilin 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NPH1; Nbla00697

Gene ID: 30010 | Gene type: protein coding

About NXPH1

Cytogenetic location: 7p21.3 Genomic coordinates (GRCh38): 7:8,433,609-8,752,961 (from NCBI)

This gene has 5 transcripts (splice variants), 272 orthologues and 3 paralogues. Biased expression in adrenal (RPKM 15.5) and brain (RPKM 12.8).

Summary

This gene is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. [provided by RefSeq, Jul 2008]

NXPH1 Products(1)

mRNA Protein Name
NM_152745.3 NP_689958.1 neurexophilin-1 precursor

NXPH1 Protein Structure

Neurexophilin

Neurexophilin: Neurexophilin (66 - 271)

  • 0
  • 100
  • 200
  • 271 a.a.
Protein Preferred Names Protein Names

neurexophilin-1

Recombinant NXPH1 Proteins

Cat. No. Product Name Accession Purity
HY-P71178 NXPH1 Protein, Human (HEK293, His) P58417 (A22-G271) ≥95%

Related Diseases

Diseases Alias
Constipation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09717 NXPH1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NXPH1 MGD MGI:107492
Bos taurus NXPH1 VGNC VGNC:50069
Felis catus NXPH1 VGNC VGNC:63939
Rattus norvegicus NXPH1 RGD RGD:3218
Canis familiaris NXPH1 VGNC VGNC:44077
Macaca mulatta NXPH1 VGNC VGNC:81732
Others NXPH1 NCBI