Atp6ap2 - ATPase H+ transporting accessory protein 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 302526

Summary

Predicted to enable signaling receptor activity. Predicted to be involved in several processes, including angiotensin maturation; nervous system development; and regulation of signal transduction. Located in several cellular components, including apical plasma membrane; cell body; and extracellular space. Biomarker of hypertension. Human ortholog(s) of this gene implicated in X-linked parkinsonism-spasticity syndrome; congenital disorder of glycosylation type II; and syndromic X-linked intellectual disability Hedera type. Orthologous to human ATP6AP2 (ATPase H+ transporting accessory protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Atp6ap2 Products (1)

mRNA Protein Name
NM_001007091.1 NP_001007092.1 renin receptor precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
21321306 RGD
located in cell body IDA
IDA: Inferred from direct assay
18326551 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
21321306 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
32165585 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
32165585 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

renin receptor

  • ATPase, H(+)-transporting, lysosomal-interacting protein 2

  • ATPase, H+ transporting, lysosomal accessory protein 2

  • renin/prorenin receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01215 ATP6AP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19275 Atp6ap2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25764 Atp6ap2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp6ap2 NCBI NCBI:10159