PLA2G2E - phospholipase A2 group IIE Gene

Homo sapiens

Also known as sPLA2-IIE; GIIE sPLA2

Gene ID: 30814 | Gene type: protein coding

About PLA2G2E

Cytogenetic location: 1p36.13 Genomic coordinates (GRCh38): 1:19,920,009-19,923,617 (from NCBI)

This gene has 1 transcript (splice variant), 139 orthologues and 8 paralogues. Low expression observed in reference dataset.

Summary

Enables calcium ion binding activity and calcium-dependent Phospholipase A2 activity. Predicted to be involved in phospholipid metabolic process. Predicted to act upstream of or within low-density lipoprotein particle remodeling. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PLA2G2E Products(1)

mRNA	Protein	Name
NM_014589.3	NP_055404.1	group IIE secretory phospholipase A2 precursor

PLA2G2E Protein Structure

Phospholip_A2_1

0
100
142 a.a.

Protein Preferred Names

Protein Names

group IIE secretory phospholipase A2

phosphatidylcholine 2-acylhydrolase 2E

Related Diseases

Diseases

Alias

Benign Secondary Hypertension

Benign Renovascular Hypertension

Inflammatory Bowel Disease 6

IBD6

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10623	PLA2G2E Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PLA2G2E	VGNC	VGNC:32957
Mus musculus	PLA2G2E	MGD	MGI:1349660
Canis familiaris	PLA2G2E	VGNC	VGNC:103648
Macaca mulatta	PLA2G2E	VGNC	VGNC:106473
Rattus norvegicus	PLA2G2E	RGD	RGD:1309611
Others	PLA2G2E	NCBI

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