Il1rapl1 - interleukin 1 receptor accessory protein-like 1 Gene

Also Known as Il1rapl

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 317553

Summary

Predicted to enable signaling receptor binding activity. Involved in negative regulation of exocytosis and regulation of neuron projection development. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability 21. Orthologous to human IL1RAPL1 (interleukin 1 receptor accessory protein like 1). [provided by Alliance of Genome Resources, Apr 2022]

Il1rapl1 Products (1)

mRNA Protein Name
NM_177935.2 NP_808796.1 interleukin-1 receptor accessory protein-like 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in negative regulation of exocytosis IDA
IDA: Inferred from direct assay
17502602 RGD
involved in regulation of neuron projection development IDA
IDA: Inferred from direct assay
17502602 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20096586 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
20096586 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-1 receptor accessory protein-like 1

  • IL-1-RAPL-1

  • IL-1RAPL-1

  • IL1RAPL-1

  • X-linked interleukin-1 receptor accessory protein-like 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06723 IL1RAPL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17932 Il1rapl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24402 Il1rapl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991468 IMM20324 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il1rapl1 NCBI NCBI:11141