Rps6kb2 - ribosomal protein S6 kinase B2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361696

About Rps6kb2

Primary_assembly 1: 201,451,265-201,458,078 reverse strand.mRatBN7.2:CM026974.1

This gene has 3 transcripts (splice variants), 199 orthologues, 7 paralogues and is associated with 3 phenotypes. Biased expression in Thymus (RPKM 11.7), Lung (RPKM 72.2) and 9 other tissues.

Summary

Enables ATP binding activity; peptide binding activity; and ribosomal protein S6 kinase activity. Involved in protein phosphorylation. Predicted to be located in ribosome. Predicted to be active in cytoplasm and nucleus. Orthologous to human RPS6KB2 (ribosomal protein S6 kinase B2). [provided by Alliance of Genome Resources, Apr 2022]

Rps6kb2 Products (1)

mRNA Protein Name
NM_001010962.2 NP_001010962.2 ribosomal protein S6 kinase beta-2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
11574531 RGD
enables peptide binding IDA
IDA: Inferred from direct assay
11431469 RGD
enables protein kinase activity IDA
IDA: Inferred from direct assay
11431469 RGD
enables ribosomal protein S6 kinase activity IMP
IMP: Inferred from mutant phenotype
11574531 RGD
Biological Process GO Annotation Evidence References Source
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
11431469 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Rps6kb2 Protein Structure

STKc_p70S6K

STKc_p70S6K: cd05584 (69 - 391)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 485 a.a.
Protein Preferred Names Protein Names

ribosomal protein S6 kinase beta-2

  • ribosomal protein S6 kinase, 70kDa, polypeptide 2

  • ribosomal protein S6 kinase, polypeptide 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12265 RPS6KB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12266 Rps6kb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12267 Rps6kb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rps6kb2 NCBI NCBI:6199