Trim56 - tripartite motif-containing 56 Gene

Also Known as Gm452; RNF109; A130009K11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 384309

Summary

Enables ubiquitin protein Ligase activity. Involved in several processes, including defense response to Other organism; positive regulation of interferon-beta production; and protein K63-linked ubiquitination. Located in cytoplasm. Orthologous to human TRIM56 (tripartite motif containing 56). [provided by Alliance of Genome Resources, Apr 2022]

Trim56 Products (1)

mRNA Protein Name
NM_201373.4 NP_958761.1 E3 ubiquitin-protein ligase TRIM56
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21074459 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
21074459 MGI
Biological Process GO Annotation Evidence References Source
involved in defense response to virus IDA
IDA: Inferred from direct assay
29426904 MGI
involved in defense response to virus IMP
IMP: Inferred from mutant phenotype
21074459 MGI
involved in innate immune response IDA
IDA: Inferred from direct assay
18248090 MGI
involved in negative regulation of viral entry into host cell IDA
IDA: Inferred from direct assay
18248090 MGI
involved in positive regulation of interferon-beta production IMP
IMP: Inferred from mutant phenotype
21074459 MGI
involved in positive regulation of type I interferon-mediated signaling pathway IDA
IDA: Inferred from direct assay
29426904 MGI
involved in protein K63-linked ubiquitination IDA
IDA: Inferred from direct assay
21074459 MGI
involved in protein monoubiquitination IDA
IDA: Inferred from direct assay
29426904 MGI
involved in response to type I interferon IDA
IDA: Inferred from direct assay
21074459 MGI
involved in suppression of viral release by host IDA
IDA: Inferred from direct assay
18248090 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21074459 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM56

  • RING-type E3 ubiquitin transferase TRIM56

  • tripartite motif-containing protein 56

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim56 NCBI NCBI:81844